Prostaglandins in the human uterus: an interaction between endometrium and myometrium
Lab / animal
OA: closed
CC0
⤵ 11 in-corpus citations
AI-generated summary
This study investigated the interplay between the human endometrium and myometrium, focusing on the role of prostaglandins in their interaction.
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Abstract
The interaction between the prostaglandin production of the human endometrium and myometrium has been further investigated using intact pieces of endometrium in homogenates of myometrium. There was an increase in the production of 6 oxo PGF, alpha when these tissues were incubated together, whereas there was no change in the production of PGE, PGF2 alpha or 13, 14 dihydro 15 - keto PGF2 alpha. This endometrial - myometrial interaction could have important implications in the pathogenesis of menorrhagia.
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Citation neighborhood (2-hop)
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References (20)
- Dating the Endometrial Biopsy via openalex
- Efficacy of mefenamic acid in patients with a complaint of menorrhagia via openalex
- Prostaglandin synthesis in the endometrium of women with ovular dysfunctional uterine bleeding via openalex
- Studies in the involvement of prostaglandins in uterine symptomatology and pathology via openalex
- Suppression of concentration of endometrial prostaglandin in early intra-uterine and ectopic pregnancy in women via openalex
- The relationship between menstrual blood loss and prostaglandin production in the human: evidence for increased availability of arachidonic acid in women suffering from menorrhagia via openalex
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Cited by (11)
- Abnormal vaginal bleeding after epidural steroid injection: a paired observation cohort study 2013
- Differential expression of cyclooxygenase-1 and -2 proteins in rat uterus and cervix during the estrous cycle, pregnancy, labor and in myometrial cells 1996
- Benign Diseases of the Endometrium 1994
- Effects of mefenamic acid on menstrual hemostasis in essential menorrhagia 1992
- Management of cyclical menorrhagia with prostaglandin synthetase inhibitor 1990
- Menorrhagia 1990
- Dysfunctional uterine bleeding 1989
- Control of menorrhagia by the cyclo-oxygenase inhibitors naproxen sodium and mefenamic acid 1987
- Control of menorrhagia by the cyclo-oxygenase inhibitors naproxen sodium and mefenamic acid 1987
- Prostaglandin production by human myometrium, uterine cervix and leiomyoma 1987
- The role of prostaglandins and allied substances in uterine haemostasis 1987
SciLite annotations
chemicals 2
prostaglandin
prostaglandin
organisms 2
human
human
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:43:36.154433+00:00
- scilite
- last seen: 2026-05-18T04:57:49.680383+00:00
- unpaywall
- last seen: 2026-10-13T06:25:51.201866+00:00
License: CC0
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