Benign Diseases of the Endometrium

In: Blaustein’s Pathology of the Female Genital Tract · 1994 · pp. 367–409 · doi:10.1007/978-1-4757-3889-6_10 · W4210992024
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This review covers benign endometrial diseases, including congenital and acquired conditions of the uterine corpus, which can reflect hormonal axis disorders and present as abnormal uterine bleeding.

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This chapter surveys benign diseases affecting the endometrium, ranging from rare infections to common polyps, and notes that because the uterus responds to hormonal stimulation, endometrial morphology can also reflect disorders of the hypothalamic-pituitary-ovarian axis and effects of exogenous hormone medications. It describes how histologic alterations are typically associated with abnormal uterine bleeding and that endometrial biopsy or curettage is commonly used both to determine causes of excessive bleeding and as an important component of infertility work-ups, while also emphasizing that hyperplasia and carcinoma may occur alongside benign conditions. The main limitation is that it is a narrative chapter directing readers to other texts for more comprehensive guidance on interpreting biopsies and curettings. Relevance to endometriosis: it does not specifically discuss endometriosis or adenomyosis, but it is included in the corpus via broader endometrial pathology/gynecologic bleeding keyword overlap.

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Abstract

A wide variety of benign diseases, from rare infections to commonplace polyps, occur in the endometrium. Furthermore, since the uterus is a target organ for hormonal stimulation, morphologic changes involving the endometrium may reflect disorders in the hypothalamic-pituitary-ovarian axis and the effects of exogenous hormone medications. The histological alterations are typically manifested by abnormal uterine bleeding, and an endometrial biopsy or curettage is commonly performed to determine its cause and to control excessive bleeding. The endometrial biopsyalso continues to be an important and integral part of the infertility work-up. Consequently, it is necessary to be aware of the wide variety of benign diseases as well as hyperplasia and carcinoma that may affect the endometrium. This chapter considers various benign, congenital, and acquired conditions involving the uterine corpus. For a more comprehensive discussion of the interpretation of these various diseases in endometrial biopsies and curettings, the reader is directed to a text that specifically addresses these issues.146. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Preview Unable to display preview. Download preview PDF. Similar content being viewed by others

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Am J Pathol 171: 419 Editor information Editors and Affiliations Rights and permissions Copyright information © 1994 Springer Science+Business Media New York About this chapter Cite this chapter Kurman, R.J., Mazur, M.T. (1994). Benign Diseases of the Endometrium. In: Kurman, R.J. (eds) Blaustein’s Pathology of the Female Genital Tract. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3889-6_10 Download citation DOI: https://doi.org/10.1007/978-1-4757-3889-6_10 Publisher Name: Springer, New York, NY Print ISBN: 978-1-4757-3891-9 Online ISBN: 978-1-4757-3889-6 eBook Packages: Springer Book Archive

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