Endometritis does not predict reproductive morbidity after pelvic inflammatory disease

Catherine L. Haggerty, Roberta B. Ness, Antonio J. Amortegui, Antonio Amortegui, Susan L. Hendrix, Sharon L. Hillier, Robert L. Holley, Jeffrey F. Peipert, Jeffrey Peipert, Hugh Randall, Steven J. Sondheimer, David E. Soper, Richard L. Sweet, Guiliana Trucco
American journal of obstetrics and gynecology · 2003 · vol. 188(1) , pp. 141–148 · doi:10.1067/mob.2003.87 · PMID:12548208 · W2049954082
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This study investigated whether endometritis predicts reproductive morbidity following pelvic inflammatory disease and found no predictive relationship.

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Abstract

OBJECTIVE: We investigated the association between endometritis and reproductive morbidity. STUDY DESIGN: Participants were 614 women in the PID Evaluation and Clinical Health (PEACH) Study with pelvic pain, pelvic organ tenderness, and leukorrhea, mucopurulent cervicitis, or untreated cervicitis. We compared women with endometritis (>or=5 neutrophils or >or=2 plasma cells), Neisseria gonorrhoeae or Chlamydia trachomatis upper genital tract infection (UGTI) or both to women without endometritis/UGTI for outcomes of pregnancy, infertility, recurrent pelvic inflammatory disease (PID), and chronic pelvic pain (CPP), adjusting for age, race, education, PID history, and baseline infertility. RESULTS: Endometritis/UGTI was not associated with reduced pregnancy (odds ratio [OR] 0.8, 95% CI 0.6-1.2) or elevated infertility (OR 1.0, 95% CI 0.6-1.6), recurrent PID (OR 0.6, 95% CI 0.4-0.9), or CPP (OR 0.6, 95% CI 0.4-0.9). PEACH participants with and without endometritis/UGTI had higher age- and race-specific pregnancy rates than 1997 national rates. CONCLUSION: Among women with clinically suspected mild-to-moderate PID treated with standard antibiotics, endometritis/UGTI was not associated with reproductive morbidity.

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Condition tags

disambig:endometritis

MeSH descriptors

Endometritis Infertility, Female Pelvic Inflammatory Disease Adolescent Adult Anti-Bacterial Agents Anti-Bacterial Agents Bacteria, Anaerobic Bacterial Infections Bacterial Infections Cefoxitin Cefoxitin Cefoxitin Chlamydia Infections Chlamydia Infections Doxycycline Doxycycline Doxycycline Endometritis Endometrium

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (31)

Cited by (14)

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