Malignant transformation in endometriosis of the urinary bladder: case report of clear cell adenocarcinoma
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This case report describes a rare instance of clear cell adenocarcinoma arising from endometriosis in the urinary bladder, confirming a link between endometriosis and this tumor type in the urinary tract.
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Abstract
Clear cell adenocarcinoma of the urinary bladder is a very rare neoplasm. This mullerian tumor frequently arises from ovarian endometriosis. We present a case of clear cell adenocarcinoma arising from endometriosis in the bladder; this is only the third such case report in the English language literature. Endometriosis involves the bladder in only approximately 1% of patients with this disease. The patient is a 40 year-old woman who has a history of adenocarcinoma arising from endometrial tissue in the bladder. Her tumor invaded the rectum, necessitating an anterior resection of the rectum as well as a partial cystectomy and a right oophorectomy. This case confirms that the relationship between endometriosis and clear cell adenocarcinomas of the female genital tract extends to the urinary bladder. Carboplatin chemotherapy was initiated in this patient.
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Cited by (22)
- Endometriosis-associated primary clear cell adenocarcinoma of the urinary bladder: A case report and literature review 2024
- Vesical clear cell adenocarcinoma of Müllerian origin treated conservatively with partial cystectomy 2022
- Mullerianosis: A Rare Tumor Like Lesion of the Urinary Bladder 2022
- Mullerianosis of the urinary bladder; A case report 2021
- Malignancies Associated with Extraovarian Endometriosis: A Literature Review 2021
- Endometriosis-associated Extraovarian Malignancies: A Challenging Question for the Clinician and the Pathologist 2020
- Endometriosis: seeking optimal management in women approaching menopause 2019
- A rare case of primary clear-cell adenocarcinoma of the bladder arising from bladder endometriosis 2015
- Endometrioid adenocarcinoma arising from deep infiltrating endometriosis involving the bladder: A case report and review of the literature 2015
- Novel insights on the malignant transformation of endometriosis into ovarian carcinoma 2014
- Malignant transformation of endometriosis within the urinary bladder 2012
- Endometriosis ureteral y vesical 2012
- Endométriose urétérale et vésicale 2012
- Mullerianosis of the urinary bladder: report of a case with diagnosis suggested in urine cytology and review of literature 2011
- Laparoscopic partial cystectomy in the management of bladder endometriosis: A case report 2009
- A case of bladder endometriosis successfully treated by laparoscopic resection 2008
- Laparoscopic management of vaginal clear cell adenocarcinoma arising in pelvic endometriosis: case report and literature review 2006
- [Bladder endometriosis. Report of two cases and bibliographic review, with special focus on Spanish articles] 2006
- Malignant extraovarian endometriosis: a review 2005
- [Clinicopathological correlation in bladder endometriosis] 2005
- Endometrioid carcinoma of the urinary bladder complicating vesical Mullerianosis: a case report and review of the literature 2004
- Is insulin resistance an essential component of PCOS?: The endometriosis syndromes: a clinical classification in the presence of aetiological confusion and therapeutic anarchy 2004
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- europepmc
- last seen: 2026-10-17T06:09:56.316927+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:59:49.088203+00:00
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