Mullerianosis of the urinary bladder: Report of a case with diagnosis suggested in urine cytology and review of literature

Hui Guan, Dorothy L Rosenthal, Yener S Erozan
Diagnostic cytopathology · 2011 · vol. 40(11) , pp. 997–1001 · doi:10.1002/dc.21693 · PMID:21538955 · W2162296653
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This case report and literature review describes mullerianosis of the urinary bladder, a rare condition characterized by benign mullerian tissues in the bladder wall, and highlights its initial suggestion by urine cytology.

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Abstract

Mullerianosis of the urinary bladder is a rare entity characterized by the presence of an admixture of at least two types of mullerian tissue in the muscularis propria of the bladder. We report a case of mullerianosis of the urinary bladder in a 28-year-old nulliparous woman with no history of pelvic surgery or endometriosis, and the diagnosis of mullerianosis was suggested initially in urine cytopathology report. In this study, previously reported cases of mullerianosis of urinary bladder are reviewed, and differential diagnosis of endometrial-like cells in the urine has been discussed. Fewer than 20 cases of mullerianosis of the urinary bladder have been reported in the literature, and only one of these cases had cytological description in a urine specimen. Most of patients were of reproductive age ranging from 28 to 53 years and had no previous history of pelvic surgery or Cesarean section. The clinical presentations frequently were abdominal/pelvic pain and dysuria/hematuria, which may or may not be associated with menstruation. Radiologic study revealed polypoid, mass-like lesion ranging from 1 to 4.5 cm in size, predominantly involving the dome or posterior wall of the bladder. Histological sections showed two or more of the three related benign mullerian glandular epithelial proliferations-endometriosis, endosalpingiosis, and endocervicosis. Most of the patients have good prognosis with medical management.

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Condition tags

endometriosis

MeSH descriptors

Rare Diseases Urinalysis Urinary Bladder Urinary Bladder Diseases Adult Cytodiagnosis Endometriosis Endometriosis Endometrium Endometrium Epithelium Epithelium Female Humans Mullerian Ducts Mullerian Ducts Rare Diseases Urinalysis Urinary Bladder Urinary Bladder Diseases

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References (24)

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