Endometriomas: their ultrasound characteristics

Van Holsbeke C, C. Van Holsbeke, Ben Van Calster, B Van Calster, S. Guerriero, L. Savelli, D. Paladini, A A Lissoni, Lissoni AA, Alessandra Lissoni, Czekierdowski A, Artur Czekierdowski, A Czekierdowski, D. Fischerová, D Fischerova, Zhang J, Jianyi Zhang, J. Zhang, Mestdagh G, G Mestdagh, A. C. Testa, T. Bourne, L. Valentin, D. Timmerman
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2010 · vol. 35(6) , pp. 730–740 · doi:10.1002/uog.7668 · PMID:20503240 · W2168947108
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This study describes the ultrasound characteristics of endometriomas in pre- and postmenopausal patients, developing rules to distinguish them from other adnexal masses based on cyst fluid echogenicity and internal features.

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Abstract

OBJECTIVES: To describe the ultrasound characteristics of endometriomas in pre- and postmenopausal patients and to develop rules that characterize endometriomas. METHODS: All patients included in the International Ovarian Tumor Analysis (IOTA) studies were used in our analysis. Patients with an adnexal mass were scanned by experienced sonologists using a standardized research protocol. The gold standard was the histology of the surgically removed adnexal mass. The gray-scale and Doppler ultrasound characteristics of the endometriomas were compared with those of other benign and malignant masses. Based on decision-tree analysis, the existing literature and clinical experience, ultrasound rules for the detection of endometriomas were created and evaluated. RESULTS: Of all 3511 patients included in the IOTA studies, 713 (20%) had endometriomas. Fifty-one per cent of the endometriomas were unilocular cysts with ground glass echogenicity of the cyst fluid. These characteristics were found less often among other benign tumors or malignancies, or among the small set of endometriomas (4%) that were found in postmenopausal patients. Based on the decision-tree analysis, the optimal rule to detect endometriomas was 'an adnexal mass in a premenopausal patient with ground glass echogenicity of the cyst fluid, one to four locules and no papillations with detectable blood flow'. Based on clinical considerations, the following rule: 'premenopausal status, ground glass echogenicity of the cyst fluid, one to four locules and no solid parts' seems preferable. CONCLUSIONS: Several rules had a good ability to characterize endometriomas. The ultrasound characteristics of endometriomas differ between pre- and postmenopausal patients. Masses in postmenopausal women whose cystic contents have a ground glass appearance have a high risk of malignancy.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Neoplasms Adnexal Diseases Adnexal Diseases Adnexal Diseases Adolescent Adolescent Adult Adult Aged Aged Aged, 80 and over Aged, 80 and over Child Child Endometriosis Endometriosis Endometriosis Female Female

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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