Understanding the Coexistence of Adenomyosis and Uterine Fibroids in Patients with Endometriosis to Enhance Treatment and Fertility Outcomes

This study investigated the coexistence of adenomyosis and uterine fibroids in individuals diagnosed with endometriosis. This research seeks to contribute to understanding how these conditions interact, aiming to improve treatment strategies and enhance patient fertility outcomes. METHODOLOGY This study aims to evaluate 250 patients suspected of endometriosis with the help of clinical investigation and ultrasound (US). From the US study, we examined the existence of endometriosis with either uterine fibroid or adenomyosis based on patient age groups (less than 32 years, 33 to 42 years, and 43 and above). In addition, ovarian endometriosis and profoundly infiltrating endometriosis were evaluated.

US study diagnosed adenomyosis in 3.2% of cases, fibroids in 21.8%, and the coexistence of both fibroid and adenomyosis in 14.2% of the cases. Intranural fibroids were found at 11.4%, submucous fibroids 1.6% and subserous at 8.1% of the total. Patients with an age of more than 33 years were more affected by adenomyosis, uterine fibroids, and both adenomyosis and uterine fibroid. There was no statistically significant correlation between uterine diseases and endometriosis. Additionally, no correlation was found between endometriosis and the patient’s age.

Our findings indicate that women over 32 are more likely to experience these comorbidities, complicating infertility outcomes. The significant association between adenomyosis and severe endometriosis reinforces the need for comprehensive diagnostic evaluation to inform tailored treatment plans. Future research should investigate the interactions between these conditions further to improve diagnostic and therapeutic approaches. Downloads Metrics

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