Prostaglandin Synthesis Inhibitors in Menorrhagia, Intrauterine Contraceptive Device‐Induced Side Effects and Endometriosis

Olavi Ylikorkala, O Ylikorkala
Pharmacology & toxicology · 1994 · vol. 75(s2) , pp. 86–88 · doi:10.1111/j.1600-0773.1994.tb02007.x · PMID:7816792 · W2026848700
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Tolfenamic acid, a prostaglandin synthesis inhibitor, effectively prevented or alleviated menorrhagia, IUD side effects, and endometriosis symptoms with good tolerability and no serious side effects.

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Abstract

Primary menorrhagia, IUD side effects and endometriotic symptoms may be a result of excessive PG release in the reproductive organs. These conditions and symptoms can be prevented or markedly alleviated by a PG synthesis inhibitor, such as tolfenamic acid. This treatment, which is used only intermittently, has been well tolerated with no serious side effects.

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Condition tags

endometriosis

MeSH descriptors

Cyclooxygenase Inhibitors Endometriosis Menorrhagia ortho-Aminobenzoates Cyclooxygenase Inhibitors Endometriosis Endometriosis Female Humans Intrauterine Devices Intrauterine Devices Menorrhagia Menorrhagia Menorrhagia ortho-Aminobenzoates Prostaglandin Antagonists Prostaglandins Prostaglandins Research Design

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (15)

Cited by (5)

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