Parametrial Endometriosis: The Occult Condition that Makes the Hard Harder

Mohamed Mabrouk, Mabrouk M, Diego Raimondo, Alessandro Arena, Arena A, Raffaella Iodice, Iodice R, Michele Altieri, Sutherland N, Neveta Sutherland, Paolo Salucci, Salucci P, Moro E, Elisa Moro, Renato Seracchioli
Journal of Minimally Invasive Gynecology · 2018 · vol. 26(5) , pp. 871–876 · doi:10.1016/j.jmig.2018.08.022 · PMID:30176361 · W2889317961
Observational OA: closed CC0 ⤵ 42 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This paper discusses parametrial endometriosis, a less commonly recognized form of endometriosis that can complicate gynecological surgeries.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

STUDY OBJECTIVE: Despite the enormous impact of lateral parametrial endometriosis (LPE), only a few studies have evaluated its diagnosis, prevalence, and clinical features. Our aim was to estimate the intraoperative prevalence of LPE in patients affected by deep infiltrating endometriosis (DIE) and to analyses clinical and surgical data associated with LPE. DESIGN: Retrospective cohort study (Canadian Task Force classification II-2). SETTING: Endometriosis tertiary level referral center, Sant'Orsola Academic Hospital, Bologna, Italy. PATIENTS: We included 1360 consecutive women submitted to surgery for DIE between 2007 and 2017. Patients were divided into 2 groups according to the presence (study group, n = 231) or absence (control group, n = 1129) of LPE. INTERVENTION: We retrospectively compared data records on the demographic features, preoperative data, and surgical outcomes of the 2 groups. MEASUREMENTS AND MAIN RESULTS: The intraoperative prevalence of LPE was 17%. Preoperatively, LPE patients complained of having a more severe intensity of dysmenorrhea (p <.001), more frequent voiding symptoms (p <.001), and more constipation (p = .02). At surgery, significant correlations were found with rectovaginal septum, vaginal, rectal, and ureteral involvement (p <.001). LPE patients intraoperatively presented a concomitant posterior nodule with a larger transverse diameter (p <.001). The operation time and hospital stay were longer for patients with LPE. Postoperatively, the LPE group needed self-catheterization more often than the control group at discharge (p <.001) and at the 1-month follow-up evaluation (p = .001). CONCLUSIONS: LPE is a condition that reflects a more severe manifestation of endometriosis, requiring more aggressive surgery.

My notes (saved in your browser only)

Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Constipation Dysmenorrhea Endometriosis Laparoscopy Ureter Adult Adult Constipation Constipation Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Female Female Humans Humans Intraoperative Period Intraoperative Period Italy

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (18)

Cited by (45)

Source provenance

europepmc
last seen: 2026-10-11T09:27:45.537177+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:22:53.024375+00:00
unpaywall
last seen: 2026-10-11T06:28:45.473802+00:00
License: CC0 · commercial use OK