Follicular-fluid anti-Müllerian hormone concentration is similar in patients with endometriosis compared with non-endometriotic patients

Campos CS, C S Campos, D Vaamonde, Vaamonde D, C Andreoli, Andreoli C, A C Martins, Alessandra Castro Martins, Martins AC, V K Genro, Genro VK, Vanessa Krebs Genro, Carlos Augusto Bastos de Souza, Souza CA, C A Souza, Chapon R, R Chapon, Rita de Cassia Borges Chapon, João Sabino Cunha‐Filho, J S L Cunha-Filho
Reproductive biomedicine online · 2010 · vol. 21(4) , pp. 470–473 · doi:10.1016/j.rbmo.2010.05.007 · PMID:20797901 · W2160476243
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Follicular fluid anti-Müllerian hormone concentration was similar in women with and without endometriosis, suggesting it is not a reliable marker for the condition in this specific context.

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Abstract

This cross-sectional prospective study assessed follicular-fluid anti-Müllerian hormone (AMH) concentrations in infertile patients with mild/minimal endometriosis during natural IVF. Thirty-two women participated in the study. Patients were divided into two groups: tubal obstruction without endometriosis (control group) and minimal/mild endometriosis (study group). All patients underwent laparoscopy for assessment of infertility; at the same time, any foci of endometriosis found were cauterized. AMH concentration was measured in the follicular fluid of a single follicle when it achieved pre-ovulatory maturation by ultrasensitive enzyme-linked immunosorbent assay. Likewise, AMH, FSH and inhibin B content in serum was also measured. Age (30 ± 1.3 and 32 ± 0.8 years) and body mass index (22 ± 0.6 and 22 ± 0.5 kg/m(2)), day-3 antral follicle count (11.3 ± 1.7 and 10.7 ± 1.5), serum FSH concentrations (5.4 ± 0.6 and 5.0 ± 0.3 IU/ml) and follicular-fluid AMH concentrations (1.8 ± 0.3 and 1.5 ± 0.1 ng/ml, study and control group, respectively; mean difference 0.33, 95% CI -0.21 to 0.88) were similar in both groups. This study shows that infertile patients with minimal/mild endometriosis have a similar concentration of AMH in the follicular fluid after natural IVF as compared with control subjects.

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Condition tags

endometriosis

MeSH descriptors

Anti-Mullerian Hormone Follicular Fluid Adult Anti-Mullerian Hormone Anti-Mullerian Hormone Body Mass Index Cross-Sectional Studies Endometriosis Female Fertilization in Vitro Follicle Stimulating Hormone Follicle Stimulating Hormone Follicular Fluid Humans Infertility, Female Inhibins Inhibins

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