An interesting case of polypoid endometriosis: Challenging in diagnosis

Shirali E, Behnaz Moradi, Reihaneh Mortazavi Ardestani, Soheila Sarmadi, Leila Bayani
In: Journal of Endometriosis and Pelvic Pain Disorders · 2026 · doi:10.1177/22840265261468454 · W7171161540
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This case report describes a rare presentation of polypoid endometriosis mimicking malignancy, highlighting specific imaging features on ultrasound and MRI that can aid in accurate diagnosis.

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Abstract

Objectives: Polypoid endometriosis is a rare presentation of endometriosis which may mimic various pelvic malignancies. In this study, we aim to explain a rare case and review the specific features in multiple imaging modalities for differentiating benign from malignant lesions. Case presentation: The patient was a 27-year-old woman presenting with highly vascular multiloculated solid cystic pelvic mass, separate from ovaries and uterus with high T1 signal in cystic components. There were conflicting appearances ranging from sarcoma to endometriosis related malignancy or benign endometriosis related pathology in ultrasound and MRI. After surgical excision, polypoid endometriosis was confirmed in pathology. Conclusion: The radiologists have to be familiar with imaging characteristics of polypoid endometriosis in different imaging evaluations. Imaging features such as dark T2 signal intensity, lack of diffusion restriction, and smooth border help them to make an accurate diagnosis and appropriate management.

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