Fertility and sterility

OBJECTIVE: To evaluate serum antimüllerian hormone (AMH) level modification after surgical excision of ovarian endometriomas. DESIGN: Systematic review. MEDLINE search from January 1990 to April 2012 using the combination of medical terms …

To define the role of surgery in the treatment of endometriomas, we review the literature available via PubMed and cross-reference the published data. We analyze the arguments in favor of and against surgical treatment of endometriomas and …

OBJECTIVE: To study the function of syndecan-1 (SDC1) and its potential regulator miR-10b in endometriosis. DESIGN: Experimental laboratory study. SETTING: University medical center. PATIENT(S): Not applicable. INTERVENTION(S): The huma…

OBJECTIVE: To analyze the expression of estrogen receptors α and β as well as their target genes implicated in proliferation, c-myc, cyclin D1, and GREB1, in the endometrium of women with or without endometriosis. DESIGN: Expression analys…

OBJECTIVE: To understand the role of ectopic endometriotic stromal cells in ovarian endometriosis (OEM) and the associated risks for infertility and carcinogenesis. DESIGN: Analyses of secreted proteins and gene expression using immortaliz…

The diagnosis of adenomyosis using noninvasive techniques such as vaginal ultrasounds and magnetic resonance has clear clinical applications and has renewed the interest in the pathogenesis of uterine adenomyosis. However, the research rema…

ObjectiveTo determine the relationship between progesterone receptor membrane component-1 (PGRMC1) expression and the outcome of IVF treatment.DesignA prospective study in which PGRMC1 messenger RNA (mRNA) levels, methylation status of the …

The use of aromatase inhibitors (AIs) in IVF patients remains controversial. AIs can be considered for ovulation induction for IVF in women who are normal and poor responders, are at risk of ovarian hyperstimulation syndrome or thrombosis, …

OBJECTIVE: To determine the exact nature and timing of alterations in thyroid function throughout controlled ovarian hyperstimulation (COH). DESIGN: Prospective cohort study. SETTING: University fertility clinic. PATIENT(S): Fifty-seven …

OBJECTIVE: To describe the demographics and clinical presentation of endosalpingiosis. To compare endosalpingiosis with endometriosis, particularly in regards to infertility and chronic pelvic pain. DESIGN: Retrospective analysis. SETTING…

Expression of the pluripotency factors SOX-2, OCT-4, KLF-4, and NANOG was analyzed by quantitative real-time polymerase chain reaction, immunohistochemistry, and immunofluorescence microscopy in the endometrium, myometrium, and endometrioti…

L-carnitine, when administered to young female mice, has been shown to induce a pathologic condition resembling human endometriosis accompanied by a marked degree of infertility. Thus, the use of this nutrient by young women may be a potent…

OBJECTIVE: To examine the regulation and the function of activin-A in stromal cells derived from endometrioma. DESIGN: Molecular studies. SETTING: University research laboratory. PATIENT(S): Endometrioma stromal cells (EoSC) were obtaine…

OBJECTIVE: To evaluate the effect of adenomyosis on endometrial gene expression and its correlation with clinical outcome. DESIGN: Transcriptomic analysis of the endometrium of women with adenomyosis during the window of implantation. Retr…

OBJECTIVE: To evaluate the performance of a novel biomarker, a disintegrin and metalloprotease-12 (ADAM-12), to differentiate an ectopic pregnancy (EP) from normal intrauterine pregnancies (IUPs). DESIGN: Case-control study. SETTING: Thre…

OBJECTIVE: To report a case of uncommon endometriosis located in the Nuck's duct and its laparoscopic resolution. DESIGN: Case report. SETTING: Gynecologic department at 12 de Octubre University Hospital, Madrid. PATIENT(S): A 35-year-ol…

OBJECTIVE: To determine whether infertile women have lower antral follicle counts (AFC) than age-matched normal women. DESIGN: Case-control. SETTING: Academic center. PATIENT(S): A total of 881 infertile women and 771 women from the comm…

OBJECTIVE: To evaluate the expression pattern of activin A, activin receptors, and activin modulators messenger RNA (mRNA) in the eutopic endometrium of patients with endometriosis at different phases of the menstrual cycle and to evaluate …

OBJECTIVE: To evaluate FOXP3 polymorphisms (rs3761549, rs3761548, rs2232368, rs2232366, and rs2280883) in a group of infertile women with and without endometriosis and controls. DESIGN: Case control study. SETTING: Human Reproduction Outp…

OBJECTIVE: To report a novel technique for cervical reconstruction in a patient with congenital agenesis of the cervix. DESIGN: Case report. SETTING: University-based tertiary care hospital. PATIENT(S): A woman with congenital absence of…

ObjectiveTo determine whether frozen-thawed blastocyst transfer pregnancy rates (PR) are lower in African-American compared with white women.DesignRetrospective review of frozen blastocyst cycles.SettingUniversity-based assisted reproductiv…

OBJECTIVE: To better understand the site and mode of action of aromatase inhibitors. DESIGN: Prospective study. SETTING: Academic research environment. PATIENT(S): Five eumenorrheic (without polycystic ovary syndrome), early follicular p…

OBJECTIVE: To evaluate the use of an aromatase inhibitor for the treatment of endometriosis-related chronic pelvic pain. DESIGN: Retrospective analysis. SETTING: Academic medical center outpatient reproductive endocrinology clinic. PATIE…

OBJECTIVE: To determine the role of the aromatase inhibitor letrozole in the treatment of recurrent ovarian endometrioma cases. DESIGN: Nonrandomized proof of concept study. SETTINGS: Outpatient tertiary-care center. PATIENT(S): Five pre…