BACKGROUND: Asymptomatic adenomyosis, which occurs in approximately one-third of patients, is a clinical and scientific enigma, thus being a subject of debate. Practicing physicians face unresolved questions: should they take no action or s…
BACKGROUND: The study of stress-induced phosphoprotein 1 in the pathogenesis of adenomyosis is not only of theoretical interest, but this protein may be also considered as a potential biomarker of the disease. AIM: The aim of this study was…
BACKGROUND: Uterine developmental anomalies have a negative impact on the implementation of female reproductive function, leading to a high risk of reproductive failures, premature birth, placental insufficiency, intrauterine growth retarda…
Эндометриоз — это хроническое, рецидивирующее заболевание, характеризующееся синдромом хронической тазовой боли и бесплодием, что существенно снижает качество жизни больных. Несмотря на высокую эффективность хирургического лечения, удалени…
BACKGROUND: Growth factors play an important role in the pathogenesis of genital endometriosis. Insulin and insulin-like growth factors are involved in mitosis and differentiation in the endometrium during the menstrual cycle and early preg…
Genital endometriosis (GE) is a widespread multifactorial disease thus making it necessary to carry on studying its pathogeny in order to work out target therapy techniques. Studying vitamin D role in GE pathogeny is a new promising researc…
ЦЕЛЬ ИССЛЕДОВАНИЯ Изучение морфологических особенностей эндометрия при гиперплазии без атипии у женщин с бесплодием, ассоциированным с наружным генитальным эндометриозом и миомой матки. МАТЕРИАЛ И МЕТОДЫ Комплексное морфологическое исследов…
Objective Genital endometriosis (GE) is a widespread gynecological disease which requires its further pathogenesis investigation and search for new effective treatments. The known data of oxytocin receptor presence in endometrioid heterotop…
Materials and methods. 28 patients with GE of I-II degrees of prevalence (R-AFS) were included in the study. Control group consisted of 11 healthy women. All the patients underwent laparoscopy and hysteroscopy with histological examination …
Background. There is no clear idea of what factors determine the characteristics of pain in endometriosis. Scientific data on the relationship between morphological and functional features of heterotopic tissue, and the intensity of the pai…
Background. A local inflammatory reaction in the endometrium caused by viral infection and associated with external genital endometriosis (EGE) can affect the implantation properties of endometrium and be one of the causes of infertility. T…
There is a violation of the secretory transformation of the endometrium during the implantation window in patients with the infertility associated with inflammatory diseases of the small pelvic organs, against the background of a high incid…