Study types
- review 4
- other 3
- article 2
Condition tags
- endometriosis 9
- infertility 2
- dyspareunia 2
- dysmenorrhea 1
Top journals
- Human Reproduction 2
- International journal of fertility 2
- Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 1
- Advances in contraception : the official journal of the Society for the Advancement of Contraception 1
- Human reproduction update 1
Frequent coauthors
- A.M. Comaru-Schally 5
- T Reissmann 3
- J Engel 2
- K Diedrich 2
- J.R. Zorn 2
- F Risquez 1
- C Tanger 1
- A. D'Acunto 1
- J P Balmaceda 1
- C Avila 1
The decapeptide LHRH antagonist, Cetrorelix, inhibits gonadotropin and sex-steroid secretion. Cetrorelix is used for IVF-ET procedures and for the treatment of benign prostatic hyperplasia, endometriosis and leiomyomas. However little is kn…
In those clinical situations in which an immediate and profound suppression of gonadotrophins is desired, LHRH agonists have the disadvantage of producing an initial stimulatory effect on hormone secretion. Therefore, the use of GnRH antago…
In the 28 years that have passed since the elucidation of the structure of luteinizing hormone-releasing hormone (LH-RH), diverse clinical applications in the field of reproductive medicine and related fields have been established for agoni…
Luteinizing hormone-releasing hormone (LHRH) plays a crucial role in controlling the ovarian cycle in women. By modification of the molecular structure of this decapeptide, analogues were synthesized with agonistic or antagonistic effects o…
Fifty patients with proven endometriosis were treated for 6 to 9 months with a delayed release preparation of microcapsules of the luteinizing hormone-releasing hormone (LH-RH) agonist D-Trp6-LH-RH, injected intramuscularly at monthly inter…
Eight menstrually cycling women with proven endometriosis were treated with a delayed-release preparation of the superactive agonist D-Trp-6-LH-RH in biodegradable microcapsules, administered intramuscularly at intervals of 16 to 36 days fo…
Reversible temporary medical oophorectomy using long-acting agonist analogs of LH-RH was tried in three infertile patients suffering from large endometriomas of the ovary. These patients had stage IV disease according to the revised 1985 cl…
Although luteinizing hormone-releasing hormone (LH-RH) agonists have been administered successfully by other than systemic routes (oral, intranasal (i.n.) and vaginal), there is no evidence that inhibitory analogues may be used in any form …