Objective: To investigate the differences in clinicopathological and molecular characteristics between pure ovarian endometrioid carcinoma (POEC) and synchronous endometrial and ovarian endometrioid carcinoma (SEOEC), aiming to provide a ba…
Abstract Study question Can a standardised hospital-school collaborative model improve early detection and multidisciplinary management of adolescent dysmenorrhea and suspected early-onset endometriosis? Summary answer Yes, this model signi…
In NSMP-EEC patients, MELF (+) is associated with various adverse clinicopathological indicators and increased recurrence risk, providing a simple and rapid morphological indicator for risk stratification. The prognosis of NSMP-EEC patients…
OBJECTIVE: To assess the association between adenomyosis volume, as a reflection of its severity, and the risk of adverse perinatal outcomes. METHODS: This multicenter retrospective cohort study was conducted at a comprehensive tertiary ca…
Background.In the bone marrow microenvironment of postmenopausal osteoporosis (PMOP), bone marrow mesenchymal stem cell (BMSC)-derived exosomal miRNAs play an important role in bone formation and bone resorption, although the pathogenesis h…
Welfare Pharmacy", which can soothe the liver and regulate qi, invigorate the spleen and nourish the blood. It is widely used in gynecology clinical practice. Professor He analyzes the specific manifestations of the disease, chooses the tre…
Background. Endometriosis (EMs) is a non-malignant gynecological disease, whose pathogenesis remains to be clarified. Recent studies have found that hypoxia induces epithelial-mesenchymal transition (EMT) as well as epigenetic modification …
Endometriosis is a chronic disease occurring during the reproductive stage of women.Although there is only limited association between endometriosis and gynecological cancers with regard to clinical features, the molecular basis of the rela…
ObjectiveAdenomyosis is a common benign gynecological disease which has some malignant behaviors. Programmed cell death 4 (PDCD4) is a newly identified tumor suppressor gene which lowly expresses in various cancers. However, the expression …
O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide ass…
OBJECTIVE: To investigate the expression and role of oxidative stress markers in the serum and follicular fluid of patients with endometriosis. MATERIALS AND METHODS: A prospective case-control study was conducted in 42 patients who underw…
SUMMARY: Polyps from the endometrium is a common cause of abnormal uterine bleeding and sometimes cause infertility and pelvic pain. The objective of this study was to measure the expression of hormone receptors (oestrogen receptor and prog…
In order to evaluate the changes of lipid perioxides (LPO) and superoxide dismutase (SOD) levels in peritoneal fluid in patients with endometriosis, the levels of LPO and SOD in peritoneal fluids from infertile women with endometriosis and …
OBJECTIVE: To investigate the correlation of endometriotic focus and peritoneal fluid as well as its effect on reproduction. METHODS: Forty-three women with surgical treatment or laproscope with infertility are divided into endometriosis g…
To study the changes of cytokines in peritoneal fluids of patients with endometriosis and their effects on reproductive activity, levels of tumor necrosis factor (TNF) and interleukin 6 (IL-6) in peritoneal fluids and peritoneal macrophages…
OBJECTIVE: To study the changes of tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) levels in peritoneal fluid of patients with endometriosis and their effects on human sperm motility and mouse embryo development. METHODS: L…
OBJECTIVE: To investigate the IL-8 and IL-10 levels in endometriosis and the regulated role of Neiyifang (NYF) on them. METHODS: Animal models with endometriosis after Cummings method was established. IL-8 and IL-10 levels were determined i…
OBJECTIVE: To investigate in vitro effect of danazol on cytokine production of macrophages in peritoneal fluid from infertile patients with endometriosis and its relationship with cytosolic free calicum ([Ca2+]i) concentration. METHODS: Per…
OBJECTIVE: To study the relationship between integrin beta 3, intracellular adhesion molecule (ICAM) and endometriosis. METHODS: The expression of integrin beta 3 and ICAM protein were determined in 3 batches by immunoblotting method in 15 …
From September 1992 to September 1993, 150 patients aged 15-68 years underwent laparoscopic gynecologic surgery. These patients included 63 patients with acute abdominal diseases (46 had ectopic pregnancy, 9 rupture of ovary, and 8 torsion …