Robert C. Bast

No ORCID on file · 7 papers in corpus · active 1989-2025

Study types

  • article 4
  • review 2
  • other 1

Condition tags

  • endometriosis 4
article 2025
·doi:10.1158/1538-7445.ovarian25-a005

Abstract Introduction: Ovarian cancer remains the most fatal gynecologic malignancy. This grim reality stems primarily from the absence of effective early detection methods, resulting in most women receiving diagnoses at advanced stages. Un…

review 2012
Endocrinology ·doi:10.1210/en.2011-2123

More than 90% of ovarian cancers have been thought to arise from epithelial cells that cover the ovarian surface or, more frequently, line subserosal cysts. Recent studies suggest that histologically similar cancers can arise from the fimbr…

other 2012
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2011.12.029

OBJECTIVE: The human epididymis protein 4 (HE4) is a novel biomarker for ovarian cancer. This study measured the HE4 and CA125 levels in women with benign gynecological disorders. STUDY DESIGN: Sera were obtained from women prior to surger…

article 2011
·doi:10.1158/1538-7445.am2011-4540

Abstract At present, epithelial ovarian cancer is the leading killer among all gynecological malignancies. Despite much research, development of this neoplasm is still not fully understood. The five-year survival rate for this disease still…

article 2004

Early detection remains the most promising approach to improve long-term survival of patients with ovarian cancer. In a five-center case-control study, serum proteomic expressions were analyzed on 153 patients with invasive epithelial ovari…

article 1994
Cancer ·doi:10.1002/1097-0142(19940401)73:7<1855::aid-cncr2820730713>3.0.co;2-#

BACKGROUND: Endometrial carcinoma is generally diagnosed only after the onset of postmenopausal bleeding. Although most patients with Stage I disease can be cured, the prognosis worsens significantly when the tumor is no longer confined to …

review 1989
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a136832

CA 125 is an antigenic determinant on a high-molecular-weight glycoprotein recognized by a monoclonal antibody which was raised using an ovarian cancer cell line as an immunogen. During the last 5 years the studies reviewed in this paper ha…