Reza Aflatoonian

Background \nGelatinases degrade extracellular matrix (ECM) components to allow for physiological remodeling and contribute to pathological tissue destruction in endometriosis. It is known that the function of gelatinases is resistant to su…

BACKGROUND: clusters are subdivided into 13 paralogous groups). OBJECTIVE: genes (A, B, C, and D) in ectopic and eutopic tissues of women with endometriosis compared to the normal endometrium. MATERIALS AND METHODS: genes was investigated b…

BACKGROUND: Establishment of a standardized animal endometriosis model is necessary for evaluation of new drug effects and for explaining different ethological aspects of this disease. For this purpose, we need a model which has more simila…

Endometriosis, which has been considered an epigenetic disease, is a prevalent gynecological disorder worldwide. With an emphasis on changes in the HOXA10 gene expression of the endometrium of women with endometriosis, the aim of this study…

PurposeThe purpose of the present study was to investigate the epigenetic mechanisms responsible for the aberrant aromatase expression (CYP19A1) in Cumulus Cells (CCs) of infertile endometriosis patients.MethodCumulus cells were obtained fr…

Endometriosis is defined as the endometrial tissue growth (containing both glandular and stromal components) on the extra uterine places especially peritoneal and visceral surfaces of the pelvis. The current medical treatments are mainly ba…

ObjectiveTo evaluate the expression of MIF, CD74, and COX-2 in normal, ectopic, and eutopic endometrium during the menstrual cycle and to assess MIF level in peripheral blood.DesignThe expressions of MIF, CD74, and COX-2 in normal, ectopic,…