Jian Li

Background: The global burden of pediatric allergic diseases continues to rise. However, clinical and public health decisions remain guided by an extensive yet fragmented evidence base characterized by substantial uncertainty, hindering th…

OBJECTIVE: To evaluate the accuracy of multimodal vaginal ultrasound in assessing post-caesarean scar healing. METHODS: A systematic review and meta-analysis were conducted on Chinese and English studies using multimodal vaginal ultrasound …

tRNA-derived small RNAs (tsRNAs) are a class of non-coding RNAs(ncRNAs) generated from precursor or mature tRNAs under stress conditions, such as starvation, hypoxia, or oxidative stress. They are broadly classified into a growing class of …

Non-suicidal self-injury (NSSI) is a prevalent and clinically urgent condition in adolescence, marked by impairments in cognitive flexibility—a capacity thought to be supported by neural variability. However, most research to date has focus…

Abstract Study question Whether renin-angiotensin system activation could be involved in endometriosis development and act as the key linking hypertension with endometriosis. Summary answer We proved that progesterone resistance related AGT…

ABSTRACT Background Emotional disturbances are common after traumatic brain injury (TBI), yet the neuroanatomic basis of these sequalae remains unclear. We aimed to determine whether emotional wellbeing is associated with the extent and/o…

Endometriosis (EMs) is a common gynecological disorder frequently associated with infertility, yet the underlying immune mechanisms remain poorly understood. Sun's Bushen Huayu Formula (BSHYF) has been clinically applied to improve fertilit…

-PIK3CA pathway. In addition, PFD attenuates the interaction of septin7-tubulin, thereby inhibiting microtubule polymerization. In summary, this study revealed a target and mechanistic insights into EC therapeutic strategies and identified …

Abstract Importance This study adopted multi-agent framework in large language models to enhance diagnosis in complex medical cases, particularly rare diseases, revealing limitation in current training and benchmarking of LLMs in healthca…

Background: Endometriosis (EMs) is a benign chronic condition that tends to recur in women of childbearing age, with an incidence of approximately 10%. It is a multifactorial disease for which the pathogenesis is currently unclear. This stu…

Background: Treatment with gonadotropin-releasing hormone (GnRH) antagonists is a powerful strategy to suppress gonadotropin activity in women with sex hormone-dependent disorders. Herein, we provide the safety, pharmacokinetics (PK), and p…

Endometriosis is a common gynecological disease among women of reproductive age, which affects approximately 6 ~10 percent of females, but the pathogenesis of endometriosis is still ambiguous. Until now, the prevailing theory concerning the…

The endomerium tissue squares of Wistar rats were autotransplanted to the surface of the peritoneum and mesometrium,then pathological changes were observed after 4 weeks.We found that difference was not significant in the survival rate and …