Izumiya C

No ORCID on file · 13 papers in corpus · active 2001-2022

Study types

  • article 10
  • other 2
  • review 1

Condition tags

  • endometriosis 13
article 2022
Peritoneal natural killer cell chemotaxis is decreased in women with pelvic endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13556

PROBLEM: NK cell and macrophage function are decreased in endometriosis, and the disease may involve reduced immune surveillance in the peritoneal cavity. NK cell cytotoxicity and migration ability (chemotaxis) are considered important; the…

article 2014
Dienogest improves human leucocyte antigen-DR underexpression and reduces tumour necrosis factor-α production in peritoneal fluid cells from women with endometriosis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2014.03.019

ObjectiveTo determine the immunological effect of dienogest (DNG), an oral anti-endometriosis drug, on peritoneal fluid (PF) macrophages collected from women with endometriosis. Although it has been suggested that DNG has direct effects on …

review 2012
Role of NK cells and HLA-G in endometriosis
Frontiers in bioscience (Scholar edition) ·doi:10.2741/s353

Impaired natural killer (NK) activity in women with endometriosis is thought to promote implantation and progression of endometrial tissue, in accord with Sampson's hypothesis. However, the mechanisms responsible for decreased NK cell activ…

other 2009
Human leukocyte antigen-G, a ligand for the natural killer receptor KIR2DL4, is expressed by eutopic endometrium only in the menstrual phase
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.12.005

OBJECTIVE: To investigate menstrual cycle changes in expression by eutopic endometrium of a nonclassic human leukocyte antigen, HLA-G, which binds to the killer immunoglobulin-like receptor (KIR) 2DL4 (CD158d) on natural killer (NK) cells. …

article 2007
Decreased human leukocyte antigen–DR expression in the lipid raft by peritoneal macrophages from women with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.02.027

ObjectiveTo investigate the macrophage response in endometriosis by determining the expression and localization of human leukocyte antigen (HLA)-ABC and HLA-DR by the peritoneal fluid (PF) macrophages and PF concentrations of interferon (IF…

article 2006
Killer Immunoglobulin‐like Receptor and Human Leukocyte Antigen Expression as Immunodiagnostic Parameters for Pelvic Endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2005.00332.x

PROBLEM: We investigated host immunologic responses to endometriosis by comparing immune cell surface antigens in peripheral blood (PB) and peritoneal fluid (PF) from women with endometriosis with those in PB and PF from other patients. MET…

other 2005
Expression of inhibitory-motif killer immunoglobulin-like receptor, KIR2DL1, is increased in natural killer cells from women with pelvic endometriosis
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2005.00271.x

PROBLEM: We investigated inhibitory and activation motif expression of killer immunoglobulin-like receptor (KIR) by natural killer (NK) cells, which may be pathogenetically involved in endometriosis. METHOD OF STUDY: We compared cells from…

article 2005
Human leukocyte antigen expression by peritoneal macrophages from women with pelvic endometriosis is depressed but coordinated with costimulatory molecule expression
Fertility and Sterility ·doi:10.1016/j.fertnstert.2004.11.039

ObjectiveTo investigate the macrophage response in endometriosis, we determined expression of human leukocyte antigen (HLA)-ABC, HLA-DR, and their costimulatory molecules by peritoneal fluid (PF) macrophages.DesignCase-control study of immu…

article 2004
Killer Inhibitory Receptor CD158a Overexpression Among Natural Killer Cells in Women With Endometriosis is Undiminished by Laparoscopic Surgery and Gonadotropin Releasing Hormone Agonist Treatment*
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2004.00170.x

PROBLEM: Natural killer (NK) dysfunction is considered to contribute to the pathogenesis of endometriosis. In this study, we investigated the host immune response to endometriosis in terms of killer inhibitory receptor (KIR) expression by N…

article 2003
Coordinated but depressed expression of human leukocyte antigen-DR, intercellular adhesion molecule-1, and CD14 on peritoneal macrophages in women with pelvic endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(03)00780-5

ObjectiveTo investigate the macrophage response in endometriosis, we determined the expression of human leukocyte antigen (HLA)-DR, intercellular adhesion molecule (ICAM)-1, and CD14 on peritoneal macrophages.DesignCase-control study of imm…

article 2002
Aberrant expression of intercellular adhesion molecule-1 and killer inhibitory receptors induces immune tolerance in women with pelvic endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(01)03249-6

ObjectiveTo investigate host immunologic response to endometriosis in terms of intercellular adhesion molecule (ICAM)-1 expression by macrophages and killer cell inhibitory receptor (KIR) expression by natural killer (NK) cells.DesignCase-c…

article 2002
Increased killer inhibitory receptor KIR2DL1 expression among natural killer cells in women with pelvic endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(01)02964-8

ObjectiveTo investigate the host immunologic response to endometriosis in terms of killer inhibitory receptor (KIR) expression by natural killer (NK) cells.DesignCase-control study of immunologic markers.SettingUniversity hospital.Patient(s…

article 2001
[Diagnosis of endometriosis].
Nihon rinsho. Japanese journal of clinical medicine