C. Richard Lyttle

No ORCID on file · 6 papers in corpus · active 1989-2004

Study types

  • article 6

Condition tags

  • endometriosis 6
  • chronic_pelvic_pain 1
  • infertility 1
  • endometrioma 1
article 2004
A selective estrogen receptor-β agonist causes lesion regression in an experimentally induced model of endometriosis
Human Reproduction ·doi:10.1093/humrep/deh711

BACKGROUND: Endometriosis is a common gynaecological problem of uncertain aetiology. It affects primarily young, reproductive-aged women and can result in chronic pelvic pain and infertility. Current approved therapies have significant side…

article 1997
Chemotaxis of macrophages by a peritoneal fluid protein in women with endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(97)81398-2

ObjectiveTo expand on a preliminary study comparing the chemotactic potential of peritoneal fluid (PF) from women with and without endometriosis and to characterize this activity via immunosuppressants and a protease.DesignCase control stud…

article 1994
Inflammatory changes of the endometrium in patients with minimal-to-moderate endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)57059-9

ObjectiveTo investigate the endometrium of normal patients for chemotactic activity to neutrophils and macrophages and compare these findings with those of patients with endometriosis.Study designEndometrial biopsies from patients with and …

article 1993
Increased chemotactic activity of peritoneal fluid in patients with endometriosis
American Journal of Obstetrics and Gynecology ·doi:10.1016/0002-9378(93)90500-i

ObjectiveOur purpose was to investigate the ability of the peritoneal fluid of patients with endometriosis to induce chemotaxis of neutrophils and macrophages.Study designPeritoneal fluid samples of patients with endometriosis (n = 20), nor…

article 1991
The effect of estradiol on the production and secretion of complement component 3 by the rat uterus and surgically induced endometriotic tissue
Fertility and Sterility ·doi:10.1016/s0015-0282(16)54135-1

We have recently demonstrated that glandular epithelial cells isolated from human endometriotic tissue synthesize and secrete complement component 3 (C3). Furthermore, because C3 is capable of producing many of the immunological activities …

article 1989
Production and Secretion of Complement Component 3 by Endometriotic Tissue*
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem-69-5-1003

Many investigators have described a variety of immune phenomena associated with endometriosis. Among these are elevated titers of activated macrophages, monokines, and lymphokines in the peritoneal fluid of patients with endometriosis. In 1…