Seung‐Yup Ku

OBJECTIVE: To investigate the influence of laparoscopic surgery on the natural conception rate in infertile women with endometriosis during the first year after the operation. METHODS: We retrospectively studied 43 infertile women with surg…

PROBLEM: To investigate the association between polymorphisms of the interleukin-1 (IL-1) family genes and endometriosis in Korean women. METHOD OF STUDY: In this case-control study, the IL-1α -889C>T, IL-1 receptor antagonist (IL-1RA) 86-b…

PROBLEM: To investigate the association between endometriosis, transforming growth factor-β1 (TGFB1) gene polymorphisms, and serum TGF-β1 levels in Korean women. METHOD OF STUDY: The -509C/T, 868T/C, 913G/C and 979G/A polymorphisms of the T…

BACKGROUND/AIMS: The aim of this study was to investigate the possibility that the K469E and G241R polymorphisms in the intercellular adhesion molecule-1 (ICAM-1) gene and the C-634G polymorphism in the interleukin (IL)-6 gene are associate…

BACKGROUND: Altered expression of endothelial nitric oxide synthase (eNOS) has been reported to be involved in the development of endometriosis. The genotypes of eNOS gene (NOS3) may be responsible for variation in its enzymatic activity as…

BACKGROUND: The purpose of this study was to investigate the potential association of the C627T polymorphism in the interleukin-2 receptor beta gene (IL-2R beta) with the risk of endometriosis in Korean women. METHODS: Two hundred and thirt…

Objective: To explore the association of the interleukin-10 (IL-10) gene -592 promoter polymorphism with endometriosis in a Korean population. Methods: This study comprised 254 women with surgically or histologically diagnosed endometriosis…

The aim of the present study was to evaluate the clinical efficacy of half-dose (50 mug) and further reduced dose (33 or 25 mug) gonadotropin-releasing hormone agonist (GnRH-a; triptorelin) long protocols for multifollicular ovarian stimula…

Objective: To explore the association of the CYP 1A1 gene polymorphism with the risk of endometriosis in a Korean population. Design: Case-control study Methods: Two-hundred fifty two Korean women with surgically or histologically diagnosed…

목적 : 한국 여성에서 에스트로겐 수용체 유전자의 dinucleotide repeat 다형성과 자궁내막증의 연관성에 대하여 조사하고자 하였다. 연구 방법 : 수술 소견 또는 조직검사상 자궁내막증으로 진단된 156명의 여성을 환자군으로 하였으며, 복강경 검사 또는 개복술을 시행하였으나 자궁내막증의 증거를 발견할 수 없었던 137명을 대조군으로 하였다. 이들에서 에스트로겐 수용체 유전자의 dinucleotide repeat 다형…

Objective : To explore the association of p53 codon 72 polymorphism with endometriosis. Methods : Two hundred seventy-one women with surgically or histologically diagnosed edometriosis of stage I-IV, and 219 patients with no evidence of end…

Objective : To explore the association of the estrogen receptor PvuII and XbaI polymorphism with endometriosis. Methods : One hundred sixty women with surgically or histologically diagnosed endometriosis of stages I-IV, and 142 patients wit…