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Endometriosis is known to be a chronic, debilitating disease. The pathophysiological mechanisms of endometriosis development include local chronic inflammation and a certain degree of local immune deficit. We investigated the relationship b…
BACKGROUND: Transvaginal and transabdominal ultrasonography has become a widely used investigative method in the diagnostic workup of endometriosis, as well as for the postoperative follow-up. The variety of lesions, the distorted anatomy c…
Ovarian endometriosis is a frequent chronic gynecological disease with an uncertain evolution regarding its progression or association with ovarian malignant lesions. The present review summarized the histological aspects, gene expression a…
Purpose of investigation: Endometriosis is a common gynecologic disease, with a genetic component, a series of studies involving different vascular endothelial growth factor (VEGF) genetic variants in endometriosis pathogenesis. In this stu…
BACKGROUND/AIM: The aim of the study was to evaluate the serum concentration of main chemokines and interferons in patients with diagnosed endometriosis. MATERIALS AND METHODS: A total of 160 women were divided in two study groups (group 1 …
BACKGROUND AND AIMS: Endometriosis is a commonly encountered disorder in women of reproductive age, consisting of the presence of active ectopic endometrial tissue outside the endometrial cavity. Surgical scar endometriosis is a rare condit…
AIM OF THE STUDY: Aim of the study was to investigate interleukin (IL)-4 serum levels in patients with advanced endometriosis and whether IL-4 promoter region (-590C/T) genetic polymorphism is involved in genetic susceptibility to endometri…
Aims. To characterize the vascularity of endometriotic cysts using color Doppler ultrasound and to differentiate more accurately between endometriotic cysts and other pelvic cyst masses. Methods. Two prospective studies were initiated: the …
THE AIM OF THE STUDY: The aim of the study was to investigate the serum pro-inflammatory cytokine profile in patients with diagnosed endometriosis. MATERIAL AND METHODS: The study included 160 women, who were divided in two study groups (Gr…
BACKGROUND: Endometriosis is a frequent gynecologic disease with a severe impact on the quality of life in the affected women; its pathogenesis is yet to be fully understood, with an altered immunity as a possible key factor. The present st…
The study's aim is to identify the Doppler profile of ovarian endometrioma. The study consists of a case-control analysis and also an analysis with type-representative sample. The case-control analysis includes two groups of patients: group…