Eleftherios P Samartzis

No ORCID on file · 12 papers in corpus · active 2011-2024

Study types

  • article 7
  • review 3
  • other 2

Condition tags

  • endometriosis 12
  • infertility 2
other 2024
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2024.08.044

Endometriosis is a disease affecting approximately 10% of reproductive age women. Loss of the tumor suppressor gene AT-rich interactive domain-containing protein 1A (ARID1A) occurs in some endometriosis cases. Histone deacetylase 6 (HDAC-6)…

review 2020
Archives of gynecology and obstetrics ·doi:10.1007/s00404-020-05445-1

BackgroundEndometriosis is one of the most common benign gynecological diseases with an occurrence approximately 10% in reproductive age. Endometriosis has been proposed as a possible precursor of certain ovarian carcinomas such as clear ce…

review 2020
Annals of translational medicine ·doi:10.21037/atm-20-3022a

Abstract: Endometriosis is a benign gynecologic condition affecting up to one woman out of ten of reproductive age. It is defined by the presence of endometrial-like tissue in localizations outside of the uterine cavity. It often causes sym…

article 2016
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1137094

Endometriosis, a painful disorder associated with infertility, is estimated to occur in approximately 7-10% of reproductive age women. Although endometriosis is considered as an estrogen-dependent disease, the role of estrogen metabolites v…

review 2013
International journal of molecular sciences ·doi:10.3390/ijms140918824

Endometriosis is a common gynecological disease affecting 6%-10% of women of reproductive age and is characterized by the presence of endometrial-like tissue in localizations outside of the uterine cavity as, e.g., endometriotic ovarian cys…

article 2013
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.05.008

ObjectiveTo investigate whether histone deacetylase inhibitors reduce the expression of the G-protein-coupled estrogen receptor (GPER) and whether the functional inhibition of GPER by the antagonist G-15 decreases the proliferation of endom…

article 2013
other 2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113488450

Class I histone deacetylases (HDACs-1-3) play an important role in steroid hormone-dependent gene expression and in modulating cell survival and proliferation. We analyzed their expression in a tissue microarray including 74 endometriosis s…

article 2013

Abstract: Endometriosis is a common gynecological disease affecting 6%–10 % of women of reproductive age and is characterized by the presence of endometrial-like tissue in localizations outside of the uterine cavity as, e.g., endometriotic …

article 2012
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-10-30

BACKGROUND: The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER expression patterns from e…

article 2012
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2011.217

Mutations of the tumor-suppressor gene ARID1A result in the loss of protein expression of the BRG-associated factor 250a (BAF250a), a large subunit of transcription-regulating Human SWI/SNF complexes, which have an important role in the con…

article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.12.058

ObjectiveTo investigate whether the histone deacetylase (HDAC) inhibitor romidepsin down-regulates VEGF (vascular endothelial growth factor) gene expression and abrogates VEGF protein secretion in human epithelial endometriotic cells.Design…