André Fedier

ORCID: 0000-0002-5613-8629 · 9 papers in corpus · active 2008-2013

Study types

  • article 7
  • other 2

Condition tags

  • endometriosis 7
  • mesh:D004715 6
  • infertility 1
article 2013
Histone deacetylase inhibitors down-regulate G-protein-coupled estrogen receptor and the GPER-antagonist G-15 inhibits proliferation in endometriotic cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.05.008
article 2013
receptor (GPER) in endometriosis: a tissue
article 2012
Expression of the G protein-coupled estrogen receptor (GPER) in endometriosis: a tissue microarray study
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-10-30

BACKGROUND: The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER expression patterns from e…

article 2012
Loss of ARID1A/BAF250a-expression in endometriosis: a biomarker for risk of carcinogenic transformation?
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2011.217
other 2011
Cordycepin (3'-deoxyadenosine), an inhibitor of mRNA polyadenylation, suppresses proliferation and activates apoptosis in human epithelial endometriotic cells in vitro
Gynecologic and obstetric investigation ·doi:10.1159/000322395

BACKGROUND/AIMS: Endometriosis is a benign but chronic disorder associated with pelvic pain and infertility. Enhanced proliferation and reduced apoptosis susceptibility are characteristics of endometriosis. Cordycepin is a poly(A) polymeras…

article 2011
Expression pattern of GPR30 in endometriosis
·doi:10.1055/s-0031-1280499

Introduction: G-protein coupled receptor 30 (GPR30) is a seven-transmembrane receptor suggested to be part of non-genomic estrogen responses that can, in contrast to the classic or genomic mode of ER action, occur rapidly within minutes. GP…

article 2011
Inhibition of transcription, expression, and secretion of the vascular epithelial growth factor in human epithelial endometriotic cells by romidepsin
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.12.058
other 2010
Romidepsin reduces histone deacetylase activity, induces acetylation of histones, inhibits proliferation, and activates apoptosis in immortalized epithelial endometriotic cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.04.052

Romidepsin inhibited HDAC activity, produced acetylation of the histone proteins, up-regulated p21, and down-regulated cyclins B1 and D1, resulting in proliferation inhibition and apoptosis activation in 11z immortalized epithelial endometr…

article 2008
Effect of histone deacetylase inhibitors on angiogenic, invasive and adhesive factors in endometriosis
·doi:10.1055/s-0028-1089326

Despite of several therapeutic options in the treatment of endometriosis, most of them are symptomatically oriented. Histone deacetylase-inhibitors (HDACi) are a novel class of epigenetic acting drugs that inhibit growth and induce apoptosi…