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Frequent coauthors
- Takashi Harada 113
- Hirakawa T 72
- Taniguchi F 68
- Naoki Terakawa 43
- Tomio Iwabe 34
- Terakawa N 29
- Masao Izawa 28
- Yukihiro Azuma 25
- Iwabe T 19
- Izawa M 16
OBJECTIVE: To investigate the clinical features of patients in Japan with malignant transformation of ovarian endometrioma. PATIENTS: Thirty-three patients diagnosed with ovarian cancer presumably arising from endometrioma were recruited re…
PROBLEM: How is the tumor necrosis factor (TNF) α-induced inhibitor of apoptosis (IAP) protein expression in endometriotic stromal cells (ESCs) involved in cell viability and signaling pathways? METHOD OF STUDY: Endometriotic stromal cells …
Endometriosis is an estrogen-dependent inflammatory disease. In endometriotic tissues, a high-estrogen environment associated with up-regulation of the aromatase gene has been well documented. There is accumulating evidence supporting a con…
ObjectiveThe objective of this study was to determine the genes that may be associated with malignant transformation of ovarian endometrioma.MethodsEndometriotic epithelial cells were isolated from tissues derived from chocolate cyst lining…
ObjectiveTo evaluate the effects of parthenolide on human endometriotic cells and murine endometriotic lesions.DesignExperimental study.SettingUniversity hospital and laboratory of animal science.Patient(s) and animal(s)Twenty women with ov…
AIMS: We investigated the potential of gonadotropin-releasing hormone (GnRH) agonists and GnRH antagonists to inhibit cell proliferation in endometriotic and endometrial stromal cells. METHODS: Twenty patients with ovarian endometriomas and…
The nuclear factor kappaB (NF-kappaB) is a ubiquitously expressed transcription factor playing vital roles in innate immunity and other processes involving cellular survival, proliferation, and differentiation. This review highlights the im…
Apoptosis is a distinctive form of programmed cell death resulting in the efficient elimination of cells without eliciting an inflammatory response. Endometriosis is characterized by the presence of endometrial cells with capacity to avoid …
ObjectiveTo search for the demethylated cytosine-phosphate-guanine (CpG) islands within the aromatase gene in stromal cells derived from endometriotic chocolate cysts.DesignProspective study.SettingDepartment of Obstetrics and Gynecology an…