Jerzy Adamski

No ORCID on file · 9 papers in corpus · active 2009-2026

Study types

  • other 3
  • review 3
  • article 2
  • preprint 1

Condition tags

  • endometriosis 9
  • mesh:D004715 3
  • infertility 1
preprint 2026
·doi:10.2139/ssrn.6872759
other 2023
Methods in enzymology ·doi:10.1016/bs.mie.2023.04.015

The 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1) has a key role in estrogen biosynthesis as it catalyzes the reduction of estrone to the most potent estrogen, estradiol. Estradiol has a high affinity for estrogen receptors and thus sti…

review 2020
Journal of personalized medicine ·doi:10.3390/jpm10040294

This systematic review analyses the contribution of metabolomics to the identification of diagnostic and prognostic biomarkers for uterine diseases. These diseases are diagnosed invasively, which entails delayed treatment and a worse clinic…

other 2016
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2016.02.023

Endometriosis is a complex, polygenic, and estrogen-dependent disease that affects 6% to 10% of women of reproductive age, and 30% to 50% of women with infertility and/or pelvic pain. Surgical diagnosis of endometriosis is still the gold st…

article 2012
Human Reproduction ·doi:10.1093/humrep/des152

BACKGROUND: Current non-invasive diagnostic methods for endometriosis lack sensitivity and specificity. In search for new diagnostic biomarkers for ovarian endometriosis, we used a hypothesis-generating targeted metabolomics approach. METHO…

review 2011
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2010.12.013

17β-Hydroxysteroid dehydrogenases (17β-HSDs) are oxidoreductases, which play a key role in estrogen and androgen steroid metabolism by catalyzing final steps of the steroid biosynthesis. Up to now, 14 different subtypes have been identified…

article 2011
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2011.03.010
other 2010
PloS one ·doi:10.1371/journal.pone.0010969

Steroid-related cancers can be treated by inhibitors of steroid metabolism. In searching for new inhibitors of human 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD 1) for the treatment of breast cancer or endometriosis, novel substa…

review 2009
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2008.12.024

The metabolism of steroids at position 17 is catalysed by a growing number of 17beta-hydroxysteroid dehydrogenases (17beta-HSDs). Several human diseases like breast or prostate cancer, endometriosis,metabolic syndrome and mental diseases we…