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BACKROUND: Endometriosis is one of the most common gynecological illnesses causing extensive psychological, physical and social impact on patient's life and exerts negative effects on health-related quality of Life (HRQoL). However, the eff…
Study question: Do cell adhesion molecules play a role in endometriosis, and can they be used as a biomarker for diagnosing endometriosis? Summary answer: Altered expression of vascular cell adhesion molecule-1 (VCAM-1) and intercellular ad…
BACKGROUND Enhanced proliferation and survival of eutopic endometrial cells from patients with endometriosis compared with healthy women is associated with abnormal activation of extra-cellular signal-regulated kinases 1 and 2 (ERK1/2). Giv…
Fragestellung: Endometriose ist eine der häufigsten gynäkologischen Erkrankungen mit einer Prävalenz von 2–10% der Frauen im gebärfähigen Alter. Ein gegenüber der Gesamtbevölkerung etwa siebenfach erhöhtes Erkrankungsrisiko in Verwandten er…
BACKGROUND: Matrix metalloproteinases (MMP) play an essential role in tissue remodelling and menstruation and appear to be regulated by cytokines such as interleukin-1alpha (IL-1alpha). In order to investigate their role in the pathogenesis…
Surgical treatment of endometriosis should be done during laparoscopy, which is obligatory for the diagnosis of the disease. In case of continuing postoperative symptoms, a medical treatment should be administered. As endometriosis is a hor…
Endometriosis is one of the most common benign gynecological diseases, affecting an estimated 10-15% of all premenopausal women. In this open multicentric prospective study, we investigated the effectiveness and tolerance of a gonadotropin …