Hiroyuki Okimura
No ORCID on file
· 19 papers in corpus
· active 2016-2026
Study types
- article 14
- review 3
- other 2
Condition tags
- endometriosis 19
- mesh:D004715 14
- endometrioma 7
- infertility 2
- adenomyosis 1
- bladder_endometriosis 1
- dysmenorrhea 1
- mesh:D004412 1
- chronic_pelvic_pain 1
- thoracic_endometriosis 1
Top journals
Frequent coauthors
- Takahide Mori 18
- Jo Kitawaki 17
- Hisashi Kataoka 15
- Fumitake Ito 15
- Akemi Koshiba 14
- Izumi Kusuki 11
- Yukiko Tanaka 11
- Eiko Maeda 10
- Yosuke Tarumi 10
- Khaleque Newaz Khan 9
review
2026
BACKGROUND: Endometriosis is increasingly recognized as a disorder of impaired reproductive immune tolerance rather than solely an endocrine disease. Although previous studies have reported inconsistent findings regarding the number of regu…
other
2025
STUDY QUESTION: Does the restoration of regulatory T cells (Tregs) suppress the progression of endometriosis? SUMMARY ANSWER: Adoptive transfer of Tregs suppresses the progression of endometriosis and reduces the levels of helper T (Th)-ce…
other
2025
OBJECTIVE: Endometriosis is an estrogen-dependent disease wherein isoflavones interact with estrogen receptors. Daidzein-rich isoflavone aglycones (DRIAs) have been shown to inhibit cell proliferation and aromatase activity in vitro and in …
article
2024
Partial cystectomy is often performed to treat bladder endometriosis. However, there are no reports of bladder rupture more than 10 years after cystectomy. A 55-year-old woman with a history of laparoscopic bilateral salpingo-oophorectomy a…
article
2023
article
2023
Menstrual blood, containing high iron levels, can undergo retrograde transport into the abdominal cavity. Excess iron causes oxidative stress and inflammation. Iron metabolism is regulated by hepcidin, and serum hepcidin levels are increase…
article
2022
article
2022
article
2022
CONTEXT: Progesterone resistance including progesterone receptor (PR) deficiency contributes to the pathophysiology of endometriosis; however, whether the PR expression levels in ovarian endometrioma (OE) correlate with the postoperative re…
article
2020
Chronic inflammation in endometriosis is associated with increased risk of future cardiovascular disease; however, no studies have investigated the cardiovascular risk of women who have undergone hormonal therapy for endometriosis. We inves…
article
2020
PROBLEM: Inflammation and immune responses play crucial roles in the development of endometriosis. Although interleukin-9 (IL-9) has a pro-inflammatory function in chronic inflammatory diseases, its function in endometriosis remains unknown…
review
2019
BACKGROUND: It has been well established that endometriosis is an estrogen-dependent disease. Although the exact pathogenesis of the disease is still unclear, it is known to be characterized by estrogen-dependent growth and maintenance of t…
article
2019
STUDY QUESTION: Is a peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α)-mediated pathway involved in the development of endometriosis? SUMMARY ANSWER: PGC-1α plays critical roles in inflammation and cell proliferation of e…
review
2018
Endometriosis is a common gynecological disease that causes various clinical symptoms, such as chronic pelvic pain, dysmenorrhea and infertility, seriously affecting women's health and their quality of life. The symptoms and endometriotic l…
article
2018
article
2018
AIM: We aimed to evaluate whether hormonal therapy immediately after postsurgical recurrence of ovarian endometrioma controls disease progression and can be an alternative therapeutic option to avoid multiple repeat surgeries. METHODS: We e…
article
2018
Malignant transformation of diaphragmatic endometriosis is rare. We present a case of endometrioid carcinoma arising from diaphragmatic endometriosis treated with laparoscopy. A 59-year-old primigravida woman who had undergone abdominal hys…
article
2017
Context: Endometriosis is a chronic inflammatory disease associated with altered immune response to endometrial cells facilitating the implantation and proliferation of ectopic endometrial tissues. Although regulatory T (Treg) cells play a …
article
2016