Wei Zhou

other 2026

Characterization of elevated levels of endometrial renin-angiotensin system components suggest a role in endometrial repair

Frontiers in endocrinology ·doi:10.3389/fendo.2026.1817846

INTRODUCTION: Each month, the endometrium is shed, regenerated, and transformed in response to changing hormone levels. These processes occur in a tightly regulated manner, and irregularities are linked with reproductive health conditions s…

article 2026

Corrigendum to "Integrative single-cell analysis reveals Bu-Shen-Huo-Xue Formula rescues iron-overloaded ovarian function via rewiring IFN-γ/JAK/STAT/CXCL10-driven immune-stromal interactions and BNIP3-mediated mitophagy in endometriosis" [Phytomedicine 2026 May:157:158343]

Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2026.158445

article 2026

Integrative single-cell analysis reveals Bu-Shen-Huo-Xue Formula rescues iron-overloaded ovarian function via rewiring IFN-γ/JAK/STAT/CXCL10-driven immune-stromal interactions and BNIP3-mediated mitophagy in endometriosis

Phytomedicine : international journal of phytotherapy and phytopharmacology ·doi:10.1016/j.phymed.2026.158343

BACKGROUND: Ovarian endometriosis (OE) is a leading cause of female infertility. Our previous work identified iron overload-driven oxidative stress and mitochondrial dysfunction in granulosa cells as key pathogenic features, yet the mechani…

article 2025

A comparison of the effects of oliceridine and sufentanil on the quality of recovery after hysteroscopic surgery: a prospective double-blind randomized controlled trial

·doi:10.1007/s00540-025-03578-8

other 2025

Expanding the genetic landscape of endometriosis: Integrative -omics analyses implicate key genes and pathways in a multi-ancestry study of over one million women

Research square ·doi:10.21203/rs.3.rs-8116602/v1

We report the findings of a genome-wide association study (GWAS) meta-analysis of endometriosis across 14 biobanks worldwide, including 32% non-European patient participants, as part of the Global Biobank Meta-Analysis Initiative (GBMI). Ou…

article 2025

Integrative Single-Cell Analysis Reveals Iron Overload-Induced Senescence and Metabolic Reprogramming in Ovarian Endometriosis-Associated Infertility

Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202417528

Endometriosis, particularly ovarian endometriosis (OE), is a major cause of infertility, often associated with reduced oocyte quality and impaired ovarian function. Iron overload plays a key role in OE progression. This study investigates t…

other 2025

ROBO3 Drives Endometriosis Progression via Dual Wnt/β-Catenin Activation and M2 Macrophage Polarization

Biological & pharmaceutical bulletin ·doi:10.1248/bpb.b25-00262

Endometriosis, a prevalent gynecological disorder marked by ectopic growth of endometrial-like tissue, demonstrates malignant tumor-like properties including aggressive adhesion and invasiveness. Emerging evidence implicates roundabout guid…

other 2024

Expanding the genetic landscape of endometriosis: Integrative -omics analyses uncover key pathways from a multi-ancestry study of over 900,000 women

medRxiv : the preprint server for health sciences ·doi:10.1101/2024.11.26.24316723

We report the findings of a genome-wide association study (GWAS) meta-analysis of endometriosis consisting of a large portion (31%) of non-European samples across 14 biobanks worldwide as part of the Global Biobank Meta-Analysis Initiative …

dataset 2023

Additional file 2 of A traditional gynecological medicine inhibits ovarian cancer progression and eliminates cancer stem cells via the LRPPRC–OXPHOS axis

·doi:10.6084/m9.figshare.23788451

Additional file 2. Data 1. Inhibition rate of natural compounds on ovarian cancer cells.

dataset 2023

Additional file 3 of A traditional gynecological medicine inhibits ovarian cancer progression and eliminates cancer stem cells via the LRPPRC–OXPHOS axis

·doi:10.6084/m9.figshare.23788454

Additional file 3. Data 2. Primer sequence.

2023

A Survey of Deep Learning-Based Lightning Prediction

·doi:10.20944/preprints202309.1232.v1

The escalation of climate change and the increasing frequency of extreme weather events have amplified the importance of precise and timely lightning prediction. This predictive capability is pivotal for the preservation of life, protection…

article 2022

Inhibition of Chemerin/CMKLR1 Axis Mitigates the Endometriosis Progression

·doi:10.2139/ssrn.4049631

article 2022

Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression

Frontiers in pharmacology ·doi:10.3389/fphar.2022.985618

Endometriosis is a common gynecological disease, characterized by the presence of endometrial-like lesions outside the uterus. This debilitating disease causes chronic pelvic pain and infertility with limited therapeutics. Chemerin is a sec…

preprint 2021

Clinical Outcomes of Sildenafil Application in Patients of Poor Endometrial Development

·doi:10.21203/rs.3.rs-560961/v1

article 2020

Dissecting the mechanism of Yuzhi Zhixue granule on ovulatory dysfunctional uterine bleeding by network pharmacology and molecular docking

Chinese medicine ·doi:10.1186/s13020-020-00392-0

BACKGROUND: Yuzhi Zhixue Granule (YZG) is a traditional Chinese patent medicine for treating excessive menstrual flow caused by ovulatory dysfunctional uterine bleeding (ODUB) accompanied by heat syndrome. However, the underlying molecular …

preprint 2020

Dissecting the Mechanism of Yuzhi Zhixue Granule on Ovulatory Dysfunctional Uterine Bleeding by Network Pharmacology and Molecular Docking

·doi:10.21203/rs.3.rs-45961/v1

Abstract Background: Yuzhi Zhixue Granule (YZG)is a traditional Chinese patent medicine for treating excessive menstrual flow caused by ovulatory dysfunctional uterine bleeding (ODUB) accompanied by heat syndrome. However, the underlying mo…

article 2017

Perfluoroalkyl substances and endometriosis-related infertility in Chinese women

Environment international ·doi:10.1016/j.envint.2017.03.003

Endometriosis is one of the main causes for female infertility. Previous studies suggested that perfluoroalkyl substances (PFASs), a group of ubiquitous environmental chemicals with properties of endocrine disruption and reproductive toxici…

2010

Chinese medicinal compound effective component for treating gynecological diseases and preparation method and application thereof