Biological & pharmaceutical bulletin

Biol Pharm Bull · ISSN (e) 1347-5215 · 2 papers in corpus

other 2025

ROBO3 Drives Endometriosis Progression via Dual Wnt/β-Catenin Activation and M2 Macrophage Polarization

doi:10.1248/bpb.b25-00262 ·PMID:41083379

Endometriosis, a prevalent gynecological disorder marked by ectopic growth of endometrial-like tissue, demonstrates malignant tumor-like properties including aggressive adhesion and invasiveness. Emerging evidence implicates roundabout guid…

article 2011

Costunolide Induces Apoptosis in Human Endometriotic Cells through Inhibition of the Prosurvival Akt and Nuclear Factor Kappa B Signaling Pathway

doi:10.1248/bpb.34.580 ·PMID:21467650

Endometriosis, a disease affecting 5-15% of women of reproductive age, is characterized by the ectopic growth of endometrial tissue. Costunolide, a sesquiterpene lactone, has anti-proliferative and pro-apoptotic activities that may be effic…