R Markham

No ORCID on file · 9 papers in corpus · active 1986-2022

Study types

  • article 6
  • other 2
  • review 1

Condition tags

  • endometriosis 9
  • mesh:D004715 8
  • infertility 4
  • dysmenorrhea 1
  • adenomyosis 1
  • dyspareunia 1
review 2022
Endometriosis Impact on Fertility: A Review of Pathogenesis, Diagnosis and Treatment
·doi:10.33140/jgrm.06.04.07

Endometriosis is a common problem affecting 5-10% of women of childbearing age. It is a condition with unknown pathology, leaving us with several theories. However, about half of women with endometriosis complain of difficulty conceiving. T…

article 2021
Circulating and Endometrial Regulatory T Cell and Related Populations in Endometriosis and Infertility: Endometriosis Is Associated with Blunting of Endometrial Cyclical Effects and Reduced Proportions in Moderate-Severe Disease
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-021-00658-4
article 2020
Comprehensive analysis utilizing flow cytometry and immunohistochemistry reveals inflammatory changes in local endometrial and systemic dendritic cell populations in endometriosis
Human Reproduction ·doi:10.1093/humrep/deaa318

STUDY QUESTION: What are the detailed endometrial tissue specific and systemic dendritic cell (DC) subset disturbances in endometriosis? SUMMARY ANSWER: This study confirms myeloid DC (mDC) and plasmacytoid DC subsets are readily identified…

other 2013
Dysregulation of vascular endothelial growth factors and their neuropilin receptors in the eutopic endometrium of women with endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113485299

Despite the importance of neuropilins (NRPs) in a number of processes that are altered in endometriosis, such as angiogenesis and neuronal guidance, these molecules have not been previously studied in the disease. Similarly, potent lymphang…

article 2011
Endometrial Stromal Cells and Immune Cell Populations Within Lymph Nodes in a Nonhuman Primate Model of Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719110397210
other 2009
Diagnosis of endometriosis by detection of nerve fibres in an endometrial biopsy: a double blind study
Human Reproduction ·doi:10.1093/humrep/dep275

BACKGROUND: Diagnosis of endometriosis currently requires a laparoscopy and this need probably contributes to the considerable average delay in diagnosis. We have reported the presence of nerve fibres in the functional layer of endometrium …

article 2005
High density of small nerve fibres in the functional layer of the endometrium in women with endometriosis
Human Reproduction ·doi:10.1093/humrep/dei368

BACKGROUND: Endometriosis is a common gynaecological disease and is frequently associated with recurrent and serious pelvic pain such as dysmenorrhoea and dyspareunia, but the mechanisms by which these symptoms are generated are not well un…

article 1989
Serum CA‐125 Levels m Women with Endometriosis
The Australian & New Zealand journal of obstetrics & gynaecology ·doi:10.1111/j.1479-828x.1989.tb01779.x

Forty-two women with laparoscopically-confirmed pelvic endometriosis (assessed according to the American Fertility Society modified classification) had serum levels of the cell-surface antigen CA-125 measured before, during and after medica…

article 1986
Measured menstrual blood loss in women with menorrhagia associated with pelvic disease or coagulation disorder.
Obstetrics and gynecology

Fifty-five women with a convincing clinical history of menorrhagia associated with recognizable pelvic disease (40 women) or a confirmed coagulation disorder (15 women) were studied through one or more cycles with measurements of menstrual …