Fujimoto VY

Research questionIs a mixture of preconception serum lipids and lipophilic micronutrients associated with clinical pregnancy and live births?DesignIn this prospective cohort study, blood serum was collected on the day of oocyte retrieval fo…

Study questionDoes the interval from delivery to initiation of a subsequent ART treatment cycle impact clinical pregnancy or live birth rates?Summary answerAn interval from delivery to treatment start of <6 months or ≥24 months is associate…

PurposeThe purpose of the study was to determine whether diagnosis of endometriosis or endometriosis with endometrioma influences in vitro fertilization (IVF) outcomes in an ethnically diverse population.MethodsWomen undergoing a first IVF …

PurposeFollicular redox balance is likely to be important for embryo quality during in vitro fertilization (IVF), and the anti-oxidative high desity lipoprotein (HDL) particle is the sole lipoprotein measured in follicular fluid (FF). There…

PurposeA hypothesis-generating pilot study exploring associations between essential trace elements measured in follicular fluid (FF) and urine and in vitro fertilization (IVF) endpoints.MethodsWe recruited 58 women undergoing IVF between 20…

The importance of high-density lipoprotein (HDL) particle components to reproduction is increasingly recognized, including the constituent paraoxonase 1 (PON1). However, the reliability characteristics of PON1 enzymes in ovarian follicular …

ObjectiveTo examine the relationship between the maternal serum bisphenol A (BPA) concentration at the time of the missed menstrual cycle and miscarriage risk.DesignRetrospective cohort of prospectively collected serum samples.SettingAcadem…

ObjectiveTo assess the variability of follicular fluid (FF) high-density lipoprotein (HDL) particle components.DesignCross-sectional design with assessment using two-stage nested analysis of variance.SettingReproductive health center.Patien…

ObjectiveTo explore the relation between bisphenol A and 14 phthalate metabolites and endometriosis.DesignMatched cohort design.SettingFourteen clinical centers.Patient(s)The operative cohort comprised 495 women undergoing laparoscopy/lapar…

ObjectiveWe sought to identify risk factors for endometriosis and their consistency across study populations in the Endometriosis: Natural History, Diagnosis, and Outcomes (ENDO) Study.Study designIn this prospective matched, exposure cohor…

PurposeWe previously reported associations between trace concentrations of Hg, Cd and Pb in blood and urine and reproductive outcomes for women undergoing in-vitro fertilization (IVF). Here we assess measurements in single follicular fluid …

BackgroundChanges in DNA methylation may play an important role in the deleterious reproductive effects reported in association with exposure to environmental pollutants. In this pilot study, we identify candidate methylation changes associ…

BACKGROUND: Environmental chemicals may be associated with endometriosis. No published research has focused on the possible role of perfluorochemicals (PFCs) despite their widespread presence in human tissues. METHODS: We formulated two sam…

BACKGROUND: An equivocal literature exists regarding the relation between persistent organochlorine pollutants (POPs) and endometriosis in women, with differences attributed to methodologies. OBJECTIVES: We assessed the association between …

ObjectiveTo determine whether frozen-thawed blastocyst transfer pregnancy rates (PR) are lower in African-American compared with white women.DesignRetrospective review of frozen blastocyst cycles.SettingUniversity-based assisted reproductiv…

ObjectiveTo estimate the incidence of endometriosis in an operative cohort of women seeking clinical care and in a matched population cohort to delineate more fully the scope and magnitude of endometriosis in the context of and beyond clini…

ObjectiveTo evaluate ethnic differences in assisted reproductive technology (ART) outcomes in the United States.DesignHistorical cohort study.SettingClinic-based data.Patient(s)A total of 139,027 ART cycles from the Society for Assisted Rep…

Common gynecologic conditions and surgeries may vary significantly by race or ethnicity. Uterine fibroid tumors are more prevalent in black women, and black women may have larger, more numerous fibroid tumors that cause worse symptoms and g…

Trace exposures to the toxic metals mercury (Hg), cadmium (Cd) and lead (Pb) may threaten human reproductive health. The aim of this study is to generate biologically-plausible hypotheses concerning associations between Hg, Cd, and Pb and i…

PurposeTo investigate whether follicular fluid lipid-soluble micronutrients are associated with embryo morphology parameters during IVF.MethodsFollicle fluid and oocytes were obtained prospectively from 81 women. Embryo morphology parameter…

BACKGROUND: Noncommunicating uterine horns are rare, occasionally presenting with functional endometrial cavities. Surgical removal of the noncommunicating horn is commonly performed to prevent endometriosis in these patients. CASE: A 41-ye…