Sugino N
No ORCID on file
· 19 papers in corpus
· active 2001-2026
Study types
- article 7
- other 2
- case-report 1
- rct 1
- review 1
Condition tags
- endometriosis 10
- infertility 4
- adenomyosis 3
- endometrioma 2
Top journals
Frequent coauthors
- Norihiro Sugino 12
- Takasaki-Kawasaki H 10
- Taketani T 10
- Hiroshi Tamura 9
- Ryo Maekawa 7
- Takasaki A 6
- Sato S 6
- Tamura I 6
- Mihara Y 5
- Isao Tamura 5
other
2026
Endometriosis is a disease characterized by fibrosis and adhesions. There are still no treatment methods targeting these conditions. One reason for this is the lack of useful animal models to investigate the mechanisms of fibrosis and adhes…
2022
Melatonin is a promising reagent that can improve assisted reproductive technology (ART) outcomes in infertility patients. However, melatonin is not effective for all infertile patients, and it remains unclear for which patients melatonin w…
article
2020
PURPOSE: To identify the upstream regulators (URs) involved in the onset and pathogenesis of ovarian endometrioma. METHODS: Recently, a method called Significance-based Modules Integrating the Transcriptome and Epigenome (SMITE) that uses t…
other
2019
Aberrant DNA methylation suppresses expression of estrogen receptor 1 (ESR1) in ovarian endometrioma
BACKGROUND: In ovarian endometriomas (OE), the expression statuses of various steroid hormone receptors are altered compared with their expression statuses in eutopic endometrium (EE). For example, in OE, the expressions of estrogen recepto…
rct
2019
BACKGROUND: Endometriosis is considered to be the most intractable cause of female infertility. Administering any type of treatment for endometriosis before in vitro fertilization and embryo transfer (IVF-ET) is an important strategy for im…
article
2017
Aim: A multicenter, retrospective survey was conducted in order to investigate the current clinical status of adenomyosis in Japan. Methods: The questionnaires covered the management of infertile women with adenomyosis and the outcomes of i…
article
2017
Purpose: To investigate the impact of adenomyosis on the complications and outcomes of pregnancy in Japan. Methods: We carried out a multicenter retrospective questionnaire survey. A questionnaire regarding pregnancy complications and the o…
2017
2017
AimAlthough a thin endometrium has been well recognized as a critical factor in implantation failure, little information is available regarding the molecular mechanisms. The present study investigated these mechanisms by using genome-wide m…
article
2015
BACKGROUND: Despite endometriosis is common estrogen dependent disease afflicting women in reproductive age, the pathogenesis has not been fully elucidated. Retinoic acid has various functions in cells as biologic modulator, and aberrant re…
article
2014
The Japan Society of Obstetrics and Gynecology Reproductive Endocrinology Committee summarizes the activities of each subcommittee below from April 2011 to March 2013. 1. Survey for clinical outcomes of infertility treatment for women with …
article
2014
BACKGROUND: Additional treatment with a gonadotropin-releasing hormone (GnRH) agonist (GnRHa) before IVF-ET (ultralong GnRHa therapy) has been reported to improve the outcome of IVF-ET in endometriosis patients. However, the mechanism of ul…
article
2014
The objective of this study was to characterize the genome-wide DNA methylation profiles of isolated endometrial stromal cells obtained from eutopic endometria with (euESCa) and without endometriosis (euESCb) and ovarian endometrial cysts (…
2014
Dynamic changes in steroidogenesis occur in ovarian granulosa cells during ovulation after the LH surge. The ovulatory LH surge induces rapid up-regulation of steroidogenic acute regulatory (StAR) protein and rapid down-regulation of aromat…
2013
BackgroundClomiphene citrate (CC) is most commonly used as a first-line treatment of infertility. However, a disturbance of endometrial growth by the adverse effects of the CC has been recognized. Since a thin endometrium is recognized as a…
2011
BackgroundBlood flow in the corpus luteum (CL) is closely related to luteal function. It is unclear how luteal blood flow is regulated. Standardized ovarian-stimulation protocol with a gonadotropin-releasing hormone agonist (GnRHa long prot…
2009
BackgroundBlood flow in the corpus luteum (CL) is associated with luteal function. The present study was undertaken to investigate whether luteal function can be improved by increasing CL blood flow in women with luteal phase defect (LFD).M…
review
2009
OBJECTIVE: To summarize the role of melatonin in the physiology and pathophysiology of the ovary. DESIGN: Review of literature. SETTING: University Health Science Center. RESULT(S): Melatonin plays an essential role in the pathogenesis o…
case-report
2001
OBJECTIVE: To report a case of 46,X,der(X)(pter-->q21::p21-->pter) with gonadal dysgenesis, tall stature, and endometriosis. DESIGN: Case report. SETTING: A university hospital. PATIENT(S): A 20-year-old primary amenorrheal woman receivi…