Shigeki Yoshida

Some women suffer from pain and infertility because of deep endometriosis. We have performed laparoscopic excision of deep endometriosis for infertile women in order to relieve pain and improve fertility. However, according to some reports,…

Spontaneous hemoperitoneum in pregnancy (SHiP) is defined as unprovoked intraperitoneal bleeding during pregnancy or up to 42 days postpartum. A 31-year-old primigravid woman presented to our hospital at 19 weeks of gestation with acute lef…

Endocervicosis is defined as an abnormal proliferation of tissues that histologically appear similar to the cervical tissues in other organs. While endocervicosis is less prevalent, it is most often found in the bladder. Herein, we present …

Endometriotic cysts often develop in the ovaries, while endometriotic nodules commonly develop in extra-ovarian sites. Herein, we report a rare case of an endometriotic cyst occurring in the mesosalpinx, and immunohistological reviews of it…

OBJECTIVE: We investigated a possible association between endometriosis and polymorphisms in the genes encoding epidermal growth factor (EGF) receptor (EGFR) and EGF in a Japanese population. METHODS: We compared the distribution of the Eg…

BACKGROUND: Vascular endothelial growth factor (VEGF) concentration in endometriosis patients is higher than controls, in serum and ascites, suggesting that VEGF may play an important role in the pathogenesis of endometriosis. In this study…

OBJECTIVE: Endometriosis is an immune-related, chronic inflammatory disease with polygenic predis-position. Cell adhesion molecules are expressed in endometriotic lesions, and in cells and tissues that are involved in the development and pr…

Endometriosis is a complex trait, which means that multiple susceptibility genes interact with one another and the environment to produce the phenotype. One of the genes previously implicated in the disease is CYP17; this encodes the enzyme…

BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) is a multifunctional proinflammatory cytokine, associated with various inflammatory and autoimmune diseases. Elevated TNF-alpha levels in peritoneal fluid have been reported in women with …