Olga Bougie

OBJECTIVE: To provide health care professionals with an evidence-based approach to the management of endometriosis and its associated symptoms. TARGET POPULATION: Women and gender-diverse individuals affected by endometriosis. BENEFITS, H…

Abstract Description Endometriosis (EM) is an inflammatory disease driven by immune dysfunction. IL-23 is a key contributor driving IL-17-producing T-helper (Th)17 cells towards a pathogenic phenotype. IL-17 and Th17 cells are elevated and …

We completed a retrospective population-based cohort study using administrative data from Ontario female patients from 1993 to 2015 to examine the association between a diagnosis of endometriosis and stroke. We identified 166 853 female pat…

STUDY OBJECTIVE: This study aimed to evaluate the association between surgeon characteristics and postoperative surgical outcomes, including rates of complications, recurrence of symptoms, fertility outcomes, and need for reoperation for in…

Endometriosis is a chronic inflammatory condition that has been linked to mental health outcomes. We conducted a population-based, retrospective, matched cohort study using administrative health data (2010-2022) from Ontario, Canada, to ass…

BACKGROUND: Endometriosis is a chronic gynecologic disorder that leads to considerable pain and a reduced quality of life. Although its physiological manifestations have been explored, its impact on mental health is less well defined. Exist…

This population-based cohort evaluated the association between endometriosis and severe maternal morbidity (SMM), and the mediating effect of infertility and fertility treatment. Included were all singleton deliveries in Ontario between 200…

OBJECTIVE: To provide a contemporary approach to the understanding of the impact and methods for the diagnosis of endometriosis in Canada. TARGET POPULATION: Individuals, families, communities, health care providers, and health care admini…

Endometriosis is a chronic inflammatory disease in which endometrial-like tissue grows ectopically, resulting in pelvic pain and infertility. IL-23 is a key contributor in the development and differentiation of TH17 cells, driving TH17 cell…

BACKGROUND: Endometriosis is a common gynecological condition with a wide range of symptoms, including infertility, dyspareunia, intestinal disorders, and pelvic pain. Laparoscopy and laparotomy are used widely for diagnosing and managing e…

BACKGROUND: A significant proportion of patients with endometriosis require surgery for management of the disease. AIMS: We aimed to assess the trend and regional variation in day surgeries for endometriosis across Canada and to identify p…

Dysmenorrhea is the most common gynecologic condition among the female population and has a significant impact on life course potential. It has a widespread impact on a female's mental and physical well-being, with longstanding impairments …

BACKGROUND: Endometriosis, a prevalent condition among females of reproductive age, may be associated with increased risk of cardiovascular disease (CVD) through chronic inflammation and early menopause. The objective of this study was to e…