Risk of Self-Harm Among Individuals Diagnosed With Endometriosis
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This study found that individuals diagnosed with endometriosis had a 42% higher risk of self-harm, overdose, or suicide compared to a matched control group, especially those without prior psychiatric care.
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Abstract
Endometriosis is a chronic inflammatory condition that has been linked to mental health outcomes. We conducted a population-based, retrospective, matched cohort study using administrative health data (2010-2022) from Ontario, Canada, to assess the risk of self-harm, overdose, and suicide in patients with endometriosis, accounting for prior psychiatric utilization. The cohort included 56,053 patients with endometriosis and 112,106 individuals in a matched control group. The primary outcome was a composite of intentional self-harm, overdose, and suicide. Endometriosis was associated with a higher risk of the composite outcome (adjusted hazard ratio 1.42, 95% CI, 1.27-1.59), particularly among individuals with no or minimal prior psychiatric care. These findings highlight the importance of considering mental health needs for patients newly diagnosed with endometriosis.
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References (5)
- Administrative health data sets to study endometriosis: a population-based approach via openalex
- Depression, Anxiety, and Self-Directed Violence in Women With Endometriosis: A Retrospective Matched-Cohort Study via openalex
- W2942339464 via openalex
- W4234160457 via openalex
- W4392219629 via openalex
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- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-06-01T00:31:08.166930+00:00
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