He J

BACKGROUND: Gallbladder cancer (GBC) is a highly aggressive malignancy with an extremely poor prognosis, and its high postoperative recurrence rate is a major challenge affecting long-term patient survival. Accurately predicting individuali…

Abdominal wall endometriosis is rare. Malignant transformation of abdominal wall endometriosis is extremely rare. We describe FDG PET/CT findings in a case of clear cell carcinoma arising from abdominal wall endometriosis with multiple lymp…

BACKGROUND: Optimal endometrial thickness and receptivity, precisely regulated by steroid hormones, are critical determinants for successful embryo implantation. Thin endometrium is a major cause of female infertility, yet its pathogenesis …

Transvaginal ultrasound-guided oocyte retrieval is routine for assisted reproduction, but unfit for some special patients. We report an elderly infertile patient with adenomyosis, whose transvaginal retrieval was high risk. Intraoperative c…

BackgroundElevated homocysteine (HCY) and hyperandrogenism are key metabolic disturbances in polycystic ovary syndrome (PCOS), but their relationship across different reproductive outcomes remains unclear.ObjectiveTo investigate outcome-spe…

BackgroundNumerous studies have suggested that assessing endometrial and subendometrial blood flow can contribute to the evaluation of endometrial receptivity. However, there remains a lack of unified expert consensus regarding the assessme…

Adenomyosis is a common gynecological disorder with incompletely understood pathogenesis. Through single-cell RNA sequencing of adenomyosis tissues, we identified epithelial-endothelial transition (EET) as a key pathological mechanism and d…

Cannabidiol (CBD), a non-psychoactive and non-addictive phytocannabinoid derived from Cannabis sativa L., has attracted increasing attention for its therapeutic potential in intestinal diseases. Accumulating evidence indicates that CBD exer…

Fibrosis is a defining feature of endometriosis (EMS). Our previous single-cell RNA sequencing (scRNA-seq) revealed myofibroblasts (MFBs) as the predominant cells in ectopic endometrium (ECE), mainly derived from fibroblast-to-myofibroblast…

BACKGROUND: Cervical pregnancy (CP) is a rare but life-threatening ectopic gestation with high risk of catastrophic hemorrhage during evacuation. Uterine artery embolization (UAE) combined with dilation and curettage (D&C) has been proposed…

BACKGROUND: Endometriosis is a chronic inflammatory disorder affecting ~ 10% of reproductive-age women, often causing pelvic pain and infertility. Despite its prevalence, diagnosis remains delayed due to non-specific symptoms and lack of re…

BackgroundNo prognostic evaluation criteria have been established for either human papillomavirus (HPV)-related cervical adenocarcinoma (HPV-CA) or HPV-independent cervical adenocarcinoma (HPV-Ind-CA). We aimed to compare and analyze the cl…

This study investigates the effects of astaxanthin on oxidative stress, mitochondrial function, and follicular development in mouse preantral follicles, with a focus on the involvement of the adenosine monophosphate-activated protein kinase…

Adding plant extracts to diets to enhance sow performance and health is widely regarded as a healthy and sustainable practice. In promoting antibiotic-free farming, plant extracts have emerged as a leading solution for enhancing sow fertili…

RationaleThe incidence of intra-abdominal hernia is very low, ranging from 0.2% to 0.9% in autopsy cases and 0.5% to 4.1% in cases of intestinal obstruction. Broad ligament hernia accounts for 4% to 7% of all cases of intra-abdominal hernia…

Uterine artery embolization (UAE) is an effective treatment for adenomyosis, but ovarian collateral supply can increase the risk of recurrence. This study aimed to explore the safety and efficacy of combined UAE and unilateral ovarian arter…

BackgroundEndoscopic gallbladder-preserving cholecystolithotomy (EGPC) has become an alternative option for treating cholecystolithiasis. However, developing a new method of EGPC in which the gallbladder wall is not damaged remains a challe…

Cancer remains a critical global health challenge, driven by tumor angiogenesis and immune evasion. Endostatin, a collagen XVIII-derived fragment, uniquely suppresses angiogenesis and reprograms the immunosuppressive tumor microenvironment …

BackgroundGrowing evidence suggests that environmental pollutants exert a detrimental impact on female fertility. Among these pollutants, volatile organic compounds (VOCs), easily encountered in the environment, have garnered significant at…

Ya-Xing Fang,1– 3,* Yu-Feng He,1– 3,* Bing-Bing Wang,1– 3,* Juan He,1,2 Yang Dong,1,2 Guo Chen,1– 3 Shu-Guang Zhou3– 6 1Department of Obstetrics and Gynecology, Maternity and Child Healthcare Hospital Affiliated to Anhui Medical…

BACKGROUND: Endometriosis (EM), a prevalent gynecological disorder in reproductive-age women, lacks reliable noninvasive diagnostic tools. EM may be detected by neutrophil extracellular traps (NETs), which are essential to inflammation and …

BackgroundZona pellucida (ZP) plays an important role in oocyte development and fertilisation, as well as in early embryo development. However, there is currently no exploration of systematic categorising and clinical treatment measures for…

BACKGROUND: To explore the impact of enhanced recovery after surgery (ERAS) optimization concept process on the perioperative period of gynecologic laparoscopic surgery. METHODS: This retrospective observational study included patients who…

BackgroundLncRNA LINC02381 has emerged as a promising tumor biomarker; however, its involvement in the pathogenesis of pancreatic cancer remains unexplored at this time. The objective of this study is to elucidate the regulatory effect of L…