Study types
- article 8
- other 4
- review 3
- case-report 1
- editorial 1
Condition tags
- endometriosis 16
- adenomyosis 5
- infertility 3
- dysmenorrhea 1
- die_deep_infiltrating 1
- chronic_pelvic_pain 1
- dyspareunia 1
Top journals
Frequent coauthors
- Regine Gaetje 17
- Manfred Kaufmann 11
- Kaufmann M 11
- Kotzian S 10
- Achim Rody 7
- Rody A 7
- Stefan Kissler 7
- Starzinski-Powitz A 5
- Knut Engels 4
- Engels K 4
Membrane proteins of the claudin superfamily are important components of cellular tight and adherens junctions. Although their exact function remains unclear, these proteins may play a role in tissue remodeling, a process which is associate…
OBJECTIVE: To characterize the expression of WNT7A in human eutopic and ectopic endometrium. DESIGN: Experimental study using real-time polymerase chain reaction, laser microdissection, in situ hybridization, and immunofluorescence. SETTI…
BACKGROUND: The metalloproteinases (MMPs) are a family of proteolytic enzymes involved in tissue remodeling and cell migration. Endometrial tissue remodeling proceeds during the menstrual cycle and requires a temporary and spatially balance…
The uterus is composed of different smooth muscle layers that serve various functions. First, menstrual debris is expulsed at the time of the menses. Second, sperm is transported in the preovulatory phase to maximize fertility, and third, t…
ObjectiveTo compare the expression of genes playing a decisive role during the embryonic development of the female genital tract (WNT4, WNT5A, WNT7A, PAX8) in the peritoneum of patients with endometriosis and control patients.DesignExperime…
The significance of retrograde menstruation as a risk factor for endometriosis has been confirmed by numerous clinical observations. Integrins mediate both cell-cell and cell-matrix adhesion, and it is therefore suspected that integrins are…
Bleeding disorders are one of the most frequent gynecological problems. The causes of bleeding disorders, and their frequency in particular, vary depending on the age of the woman affected. In premenopause and perimenopause, the most freque…
OBJECTIVE: Uterine hyperperistalsis and dysperistalsis are common phenomena in endometriosis and may be responsible for reduced fertility in cases of minimal or mild extent of disease. Since a high prevalence of adenomyosis uteri has been w…
Trotz zahlreicher wissenschaftlicher Untersuchungen ist die Pathogenese der Endometriose in ihren zentralen Punkten bis heute ungeklärt. Die aufgestellten Theorien zur Entstehung werden zwar jeweils durch eine Vielzahl klinischer Beobachtun…
Endometriosis and adenomyosis show a high prevalence and can be regarded as different symptoms of a unique disease - the dislocation of basal endometrium. Diagnostic methods for detecting adenomyosis are transvaginal sonography (TVS) or T-2…
A 53-year-old women underwent D & C and diagnostic hysteroscopy for suspected endometrial hyperplasia, when the posterior uterine wall was perforated. An endometrial polyp prolapsed into the abdominal cavity after uterine rupture which was …
ObjectiveOvarian cancer antigen CA 125 is used widely for diagnostic and therapeutic evaluation of ovarian cancer. Although the initial description of CA 125 was in 1981, its function is still unknown. In collagen gel system the invasivenes…
The aetiology and pathogenesis of endometriosis, defined as the presence of endometrium-like tissue outside the uterine cavity, is largely unknown. In this paper we present and discuss possibilities to study the putative pathogenic properti…
Endometriosis is one of the most frequent diseases in gynecology. It is a histologically defined nonmalignant disease in which endometrium-like tissue is found outside the uterus (for example, peritoneum, gut, or lung). The pathogenesis of …
OBJECTIVE: Interleukin-6 (IL-6) and soluble Interleukin-6-receptor (sIL-6R) concentrations were investigated in patients with endometriosis and other benign gynecologic diseases. METHODS: During laparoscopy or laparotomy peritoneal fluid an…
The pathogenesis of endometriosis is not known. The currently favoured theory is that viable endometrial cells, shed from the endometrium into the pelvic cavity by retrograde menstruation, reattach and invade other tissues. We used a collag…
ObjectiveAutomatic cutting needle sampling was used for diagnosis of adenomyosis uteri. The purpose of this study was the establishment of myometrial biopsy as a clinically applicable method.Study designSensitivity and specificity of myomet…