Akira Iwase

No ORCID on file · 35 papers in corpus · active 2007-2026

Study types

  • article 20
  • other 11
  • review 2
  • case-report 1
  • rct 1

Condition tags

  • endometriosis 32
  • infertility 8
  • endometrioma 6
  • chronic_pelvic_pain 1
  • dysmenorrhea 1
  • die_deep_infiltrating 1
  • bladder_endometriosis 1
other 2026
Reproductive medicine and biology ·doi:10.1002/rmb2.70048

PURPOSE: Decidualization of endometrial stromal cells involves significant morphological and functional changes in which alpha-smooth muscle actin (αSMA) expression decreases. Meflin, a glycosylphosphatidylinositol-anchored protein, suppres…

other 2026
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.70275

AIM: Endometriosis affects 6%-10% of women of reproductive age and is associated with chronic pelvic pain, infertility, and impaired quality of life. The endometriosis fertility index (EFI) predicts spontaneous pregnancy postoperatively, bu…

other 2025
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01381-4

BACKGROUND: Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertil…

other 2025
Reproductive medicine and biology ·doi:10.1002/rmb2.12675

PURPOSE: This study evaluated the feasibility of single-nucleotide polymorphism (SNP) genotyping using dried blood spot (DBS) samples stored under various conditions, based on the genotyping success rate and concordance with whole blood res…

other 2024
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15885

BACKGROUND: We aimed to examine the effects of endometriosis on the rate of abnormal placentation by comparing the data of pregnant women with and without endometriosis. METHODS: A case-control study was conducted to compare the perinatal …

other 2024
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15978

AIM: To identify factors influencing the Trendelenburg angle required during laparoscopic gynecological surgery. METHODS: Patients who underwent laparoscopic surgery at a single university hospital between May 1, 2019, and March 31, 2021 w…

other 2023
Science translational medicine ·doi:10.1126/scitranslmed.add1531

Retrograde menstruation is a widely accepted cause of endometriosis. However, not all women who experience retrograde menstruation develop endometriosis, and the mechanisms underlying these observations are not yet understood. Here, we demo…

article 2023

Retrograde menstruation is a widely accepted cause of endometriosis. However, not all women who experience retrograde menstruation develop endometriosis, and the mechanisms underlying these observations are not yet understood. Here, we demo…

article 2023
Reproductive medicine and biology ·doi:10.1002/rmb2.12536

Abstract Purpose This study aimed to investigate whether serum leucine‐rich α2‐glycoprotein (LRG) is a useful diagnostic biomarker for endometriosis, including the evaluation of treatment efficacy and exploration of LRG production in endome…

article 2023
Reproductive biology ·doi:10.1016/j.repbio.2023.100821
article 2022
·doi:10.3390/endocrines3020020

Endometriosis is one of the most common diseases in women of reproductive age, and although there are many theories to explain this enigmatic disease, such as reflux theory, metastasis theory, and metaplasia theory, there is still no single…

article 2021
·doi:10.2974/kmj.71.207

帝王切開手術瘢痕に生じた腹壁子宮内膜症の1例を経験した.患者は40代女性,半年前より月経時の周期的な痛みを伴う腹壁腫瘤を自覚し当院を受診した.2年前に帝王切開の既往があり,同手術瘢痕頭側に長径2 cmの皮下腫瘍を触知した.エコーでは腹直筋上に内部やや不均一な低エコー腫瘤を認め,MRIではT1強調画像で低信号,T2強調画像でやや高信号の結節を認めた.帝王切開手術瘢痕に生じた腹壁子宮内膜症を疑い摘出術を行った.病理組織学的検査では子宮内膜腺細胞および間質細胞を認め,腹壁子宮内膜症…

rct 2021
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00866-2

BACKGROUND: Ovarian endometrioma is a common gynecological disease that is often treated with surgery or hormonal treatment. Ovarian cystectomy, a surgical procedure for ovarian endometrioma, can result in impaired ovarian reserve. METHODS…

review 2021
·doi:10.3390/endocrines2030024

Endometriosis-associated ovarian malignancies have been well documented. Although these malignancies also occur as extraovarian lesions, little is known about them. Thus, this literature review aimed to further explore these rarely experien…

article 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00044-1
other 2020
The American journal of pathology ·doi:10.1016/j.ajpath.2019.09.008

Repeated tissue injury and repair and fibrosis play a pivotal role in endometriosis. Fibrotic tissue consists of extracellular matrix proteins, regulated by transcriptional factors promoting cell proliferation and survival. Periostin is one…

other 2020
Redox biology ·doi:10.1016/j.redox.2020.101726

Ovarian endometriosis (OE) provides women of reproductive age with not only severe menstrual pain but also infertility and an increased risk for ovarian carcinogenesis. Whereas peritoneal endometriosis models have been developed with syngen…

other 2019
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118802053

Several features exist that distinguish endometriotic cells from eutopic endometrial cells. Progesterone resistance is one of the main distinguishing features, although how progesterone resistance affects the phenotype of endometriotic cell…

article 2018
·doi:10.1016/j.fertnstert.2018.07.1098
article 2018
·doi:10.5180/jsgoe.34.2_204

Bladder endometriosis is a rare pelvic dysfunction with painful urination and hematuria.

article 2016
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-016-0210-9

BACKGROUND: Serum anti-Müllerian hormone (AMH) concentration has been used to assess ovarian reserve in patients with endometriosis, especially when endometrioma surgery is involved. Previously, we reported that decreased serum AMH levels a…

article 2016
Free radical research ·doi:10.1080/10715762.2016.1211273

Endometriosis is observed in ∼10% of reproductive age women. Ovarian endometriosis not only causes dysmenorrhea but also causes infertility and a high risk of adenocarcinoma. Due to its scattered nature, complete surgical resection is diffi…

other 2016
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2016.1157862

Pentraxin 3 (PTX3) is an inflammatory mediator that is released by a wide range of tissues and cells. Elevated PTX3 levels may represent a useful diagnostic and/or prognostic marker for a number of diseases. The purpose of this study was to…

article 2015
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.3109/09513590.2015.1114078

We assessed the associations between preoperative and postoperative serum anti-Müllerian hormone (AMH) levels and parameters of endometriosis and endometriomas surgery with the success of infertility treatments after cystectomy. Seventeen o…

article 2015
Redox biology ·doi:10.1016/j.redox.2015.10.001

Ovarian endometriosis is a recognized risk for infertility and epithelial ovarian cancer, presumably due to iron overload resulting from repeated hemorrhage. To find a clue for early detection and prevention of ovarian endometriosis-associa…