Farideh Z. Bischoff

Endometriosis is a chronic estrogen-dependent disorder affecting up to 10% of women of reproductive age, and the absence of reliable noninvasive diagnostic tools contributes to delayed diagnosis and disease progression. To identify potentia…

STUDY OBJECTIVE: To develop and validate a non-invasive, blood-based diagnostic assay for endometriosis that performs accurately across menstrual cycle phases and complements existing imaging modalities. DESIGN: Multicenter case-control st…

BACKGROUND: Endometriosis is a chronic inflammatory disorder affecting ~ 10% of reproductive-age women, often causing pelvic pain and infertility. Despite its prevalence, diagnosis remains delayed due to non-specific symptoms and lack of re…

Abstract Study question Is a reliable blood-based noninvasive diagnostic test for mild and severe endometriosis feasible using five miRNA biomarkers and have clinical utility? Summary answer Noninvasive molecular diagnosis using serum and a…

Abstract Endometriosis is a common yet often underdiagnosed condition, partly due to the lack of reliable diagnostics. This study examines the clinical feasibility of a blood-based, miRNA-driven test to diagnose endometriosis and address th…

Endometriosis is a common yet often underdiagnosed condition, partly due to the lack of reliable diagnostics. This study examines the clinical feasibility of a blood-based, miRNA-driven test to diagnose endometriosis and address the challen…

INTRODUCTION: The clinical presentation of endometriosis varies widely, from asymptomatic to severe with often infertility also presented. Screening methods today include imaging, which is subject to operator expertise and poor specificity.…

Abstract Background Endometriosis is a chronic inflammatory disorder affecting ~ 10% of reproductive-age women, often causing pelvic pain and infertility. Despite its prevalence, diagnosis remains delayed due to non-specific symptoms and l…

ObjectiveTo investigate quantitative aberrations involving p53 copy numbers in eutopic endometrial and endometriotic tissue from two populations.DesignComparative analysis of normal and diseased tissue.SettingTissue specimens collected in I…

Endometriosis is a complex gynecologic disorder that has long been recognized as showing heritable tendencies, with recurrence risks of 5-7% for first-degree relatives. Familial and epidemiologic studies support that this disease is a genet…

Endometriosis long has been recognized as showing heritable tendencies, with recurrence risks of 5% to 7% for first-degree relatives. The risk indicates that polygenic and multifactorial etiology is far more likely to be the cause than mend…

Endometriosis is inherited in polygenic/multifactorial fashion, with recurrence risks of 5-7% for first-degree relatives. The current task is to determine the number and location of causative genes. This review initially supports the basis …

Endometriosis is well established as a condition showing heritable tendencies. Polygenic/multifactorial etiology appears far more likely to be the etiology than Mendelian inheritance. The current task is to determine the number and location…

ProblemGenetic predisposition to endometriosis is well established, but the gene(s) involved largely remain unknown. Although endometriosis is considered a benign disease, it displays several features similar to malignancy: altered morpholo…

Endometriosis affects 10-15% of women of reproductive age and is a common cause of infertility and pelvic pain. Although endometriosis is characterized by abnormal growth or turn-over of cells, the genetic changes involved remain unclear. W…