Ashon Sa'adi

Endometriosis, a chronic inflammatory condition linked to pelvic pain and infertility, is characterized by immune dysfunction involving dysregulated apoptosis and cell proliferation. This case-control study included 87 infertile women under…

Background: Intramuscular abdominal wall endometriosis (AWE) refers to the ectopic implantation of functional endometrial tissue within the musculature of the abdominal wall.It is typically associated with chronic symptoms, most notably cyc…

INTRODUCTION: Pelvic pain, often associated with endometriosis, significantly affects women's quality of life. This study explored the soluble neural cell adhesion molecules (sNCAM), soluble interleukin 2 receptor α (sIL-2Rα), and IL-2 leve…

BACKGROUND: This study aimed to determine the accuracy of CYFRA 21-1 using urine creatinine correction (CYFRA/Cr) as a biomarker of endometriosis. METHODS: This study includes 73 patients from the Indonesian population, with 38 endometrios…

INTRODUCTION: Endometriosis is a chronic inflammatory disease characterized by endometrial-like tissue outside the uterus. Molecules linked to natural killer (NK) and cytotoxic T cells, including granulysin (GNLY), MHC class I-related chain…

OBJECTIVE: To investigate the association between soluble adhesion molecules (sE-cadherin, sE-selectin, sICAM-1, sVCAM-1) in serum and peritoneal fluid and pelvic pain in infertile women with endometriosis. METHODS: This observational study…

OBJECTIVES: Myeloid cell-derived factors contribute to the immunopathology of endometriosis. Soluble CD14 (sCD14), CD163 (sCD163), and MIF serve as in vivo markers of myeloid function. However, these soluble molecules are largely unexplored…

The objective of this study was to examine the effect of administering an ethanol extract obtained from basil leaves on the expression of vascular endothelial growth factor (VEGF) and the severity of endometriosis lesions in a mouse model. …

OBJECTIVE: To evaluate interleukin (IL)-1β, IL-6, IL-8, and IL-12p70 levels in serum and peritoneal fluid in women related to infertility and pelvic pain. METHODS: Eighty-seven women were diagnosed with endometriosis or cases related to inf…

Background: Endometriosis is a common benign, estrogen-dependent, and chronic gynecological disease. Immune system disturbances and inflammatory abnormalities were involved in the pathogenesis of endometriosis. , Therefore, it is logical to…

PROBLEM: Soluble immune checkpoint molecules constitute the emerging novel mediators in immune regulation. Their role in the pathogenesis of endometriosis has not been fully addressed. In this study, we aimed to investigate the relationship…

Endometriosis merupakan penyakit kandungan yang banyak diderita wanita usia reproduksi, ditandai dengan adanya jaringan endometrium baik stroma maupun kelenjar yang implantasi di luar kavum uterus dan memicu terjadinya reaksi inflamasi kron…

Background: The chronic pelvic pain as non-cyclical pain is seriousenough to cause disability or lead to medical care. While these treatmentsare very successful there is still a 20 to 25% failure rate and surgeryhas been an option for such …