Yuan Lu

No ORCID on file · 14 papers in corpus · active 2008-2023

Study types

  • article 8
  • other 3
  • review 1

Condition tags

  • endometriosis 12
  • dysmenorrhea 1
  • endometrioma 1
  • adenomyosis 1
article 2023
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2023.103304

RESEARCH QUESTION: Do sphingosine 1-phosphate (S1P) modulators have therapeutic effects on endometriosis in mice and, if they do, which receptor is responsible for these effects? DESIGN: A surgically induced endometriosis mouse model was e…

review 2023
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-023-01167-2

Endometriosis is a common condition in women of reproductive age, but its current interventions are unsatisfactory. Recent research discovered a dysregulation of the sphingosine 1-phosphate (S1P) signaling pathway in endometriosis and showe…

2022
·doi:10.1101/2022.02.07.22270599
other 2018
Medicine ·doi:10.1097/MD.0000000000010881

This retrospective analysis aimed to clarify the clinical and pathologic features of ovarian clear cell carcinoma (OCCC), and to determine the factors predictive of survival.Data waereextracted from OCCC patients who underwent primary surge…

article 2018
Journal of ovarian research ·doi:10.1186/s13048-018-0425-9

BACKGROUND: Considered as the precursor lesion of a subset of ovarian clear cell carcinoma (OCCC), the prognostic role of endometriosis in OCCC patients remains controversial. This study aimed to investigate the prognostic role of coexistin…

2016
Molecular and clinical oncology ·doi:10.3892/mco.2016.915

Bilateral malignant ovarian germ cell tumors (MOGCTs) are rare. Determination of the optimal treatment modalities is crucial, as these malignancies mainly affect girls and young women who may wish to preserve their fertility. In order to re…

article 2012
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112452940

We recently reported that Slit/Roundabout (ROBO) 1 pathway may be a constituent biomarker for recurrence of endometriosis, likely through promoting angiogenesis. In this study, we sought to determine as whether Slit2 overexpression can faci…

article 2011
·doi:10.1093/humrep/der173
article 2010
Frontiers in bioscience (Elite edition) ·doi:10.2741/e272

p50 is a member of the NF-kappaB family known to be involved in endometriosis. To gain insight into the roles of p50 in the development of endometriosis, we cross-transplanted endometrial fragments from p50 knockout mice to wild-type mice a…

article 2010
Human Reproduction ·doi:10.1093/humrep/dep472

BACKGROUND: The aim of this study was to evaluate the effect of trichostatin A (TSA) in a mouse model of endometriosis on serum tumour necrosis factor alpha (TNFalpha) levels, hotplate latency, lesion size and immunoreactivity to Trpv1, Pkc…

article 2009
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2009.11.009

OBJECTIVE: To investigate clinicopathological features of endometriosis-associated epithelial ovarian carcinoma. METHODS: Retrospective follow-up study, clinicopathological data from patients with ovarian epithelial carcinoma were retrieved…

other 2009
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.01.084

Compared with normal endometrium, progesterone receptor isoform B (PR-B) and IkappaBalpha immunoreactivity were statistically significantly reduced in ectopic as well as eutopic endometrium from women with adenomyosis while nuclear p65, p50…

article 2008
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.01.070

Cyclooxegenase-2 expression was evaluated by immunohistochemistry in endometrioma tissue samples taken from 109 patients, of whom 53 had recurrence by 30 months after surgery and 56 did not. Cyclooxegenase-2 overexpression, along with previ…

other 2008
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2008.04.040

OBJECTIVE: This study was undertaken to evaluate the immunoreactivity of progesterone receptor isoform B and nuclear factor kappa-B p65 subunit in ovarian endometrioma tissue samples harvested at the time of surgery and their relationship w…