Hakan Cakmak

No ORCID on file · 19 papers in corpus · active 2006-2023

Study types

  • article 12
  • review 4
  • other 3

Condition tags

  • endometriosis 18
  • mesh:D004715 15
  • infertility 6
  • endometrioma 1
  • adenomyosis 1
other 2023
B-cell lymphoma 6 expression significantly differs by the uterine preparation method used for frozen embryo transfer
Fertility and sterility ·doi:10.1016/j.fertnstert.2023.04.021

OBJECTIVE: To determine whether B-cell lymphoma 6 (BCL6), an endometriosis-associated marker postulated to predict poor pregnancy outcomes, is differentially expressed in the window of implantation with various uterine preparation regimens …

article 2017
p38 Mitogen-Activated Protein Kinase is Involved in the Pathogenesis of Endometriosis by Modulating Inflammation, but not Cell Survival
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117725828
article 2016
Original Articles Statins Inhibit Monocyte Chemotactic Protein 1 Expression in Endometriosis

Statins are potent inhibitors of the endogenous mevalonate pathway. Besides inhibiting cholesterol biosynthesis, statins may also demonstrate anti-inflammatory properties. Inflammation is implicated in the attachment and invasion of endomet…

article 2012
Statins Inhibit Monocyte Chemotactic Protein 1 Expression in Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719111430998
review 2010
Implantation failure: molecular mechanisms and clinical treatment
Human reproduction update ·doi:10.1093/humupd/dmq037

BACKGROUND: Implantation is a complex initial step in the establishment of a successful pregnancy. Although embryo quality is an important determinant of implantation, temporally coordinated differentiation of endometrial cells to attain ut…

review 2010
Molecular Mechanisms of Treatment Resistance in Endometriosis: The Role of Progesterone–Hox Gene Interactions
Seminars in reproductive medicine ·doi:10.1055/s-0029-1242996

HOX genes, encoding homeodomain transcription factors, are dynamically expressed in endometrium, where they are necessary for endometrial growth, differentiation, and implantation. In human endometrium, the expression of HOXA10 and HOXA11 i…

other 2009
ABO and Rh blood groups distribution in patients with endometriosis
Archives of gynecology and obstetrics ·doi:10.1007/s00404-009-1031-2

BACKGROUND: The aim of this investigation was twofold: first, to demonstrate an association between endometriosis, ABO blood groups and Rhesus factor and, second, to show potential correlation of ABO blood group and stages of endometriosis.…

article 2009
Differential regulation of Akt phosphorylation in endometriosis
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2009.10.001
article 2009
Endometriosis related to family history of malignancies in the Yale series
Surgical oncology ·doi:10.1016/j.suronc.2009.02.012
review 2009
Immune-endocrine interactions in endometriosis
Frontiers in bioscience (Elite edition) ·doi:10.2741/E39

Endocrine and immune systems are among the most essential regulators of endometrial physiology, and immune-endocrine interactions are likely to be involved in the pathogenesis of endometriosis. Endometriosis is an inflammatory, estrogen-dep…

article 2008
Arguments for a left lateral predisposition of endometrioma
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.01.059
article 2008
Extracellularly Signal-Regulated Kinase Activity in the Human Endometrium: Possible Roles in the Pathogenesis of Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2007-2051

CONTEXT: Endometriosis is an estrogen-dependent disease characterized by the presence of endometrial tissue outside of the uterine cavity, causing pelvic pain and infertility in 10% of reproductive-aged women. It is unclear why ectopic endo…

article 2008
Familial aggregation of endometriosis in the Yale Series
Archives of gynecology and obstetrics ·doi:10.1007/s00404-008-0644-1
other 2008
Increased rate of endometriosis and spontaneous abortion in an in vitro fertilization program: no correlation with epidemiological factors
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590801948341

BACKGROUND: There are conflicting data concerning endometriosis and spontaneous abortion (SAB). The aim of the present study was to evaluate if there was any association between endometriosis and SAB. Moreover, we investigated risk factors …

article 2008
The familial risk of breast cancer in women with endometriosis from Yale series
Surgical oncology ·doi:10.1016/j.suronc.2008.01.002
article 2007
Epidemiological characteristics in women with and without endometriosis in the Yale series
Archives of gynecology and obstetrics ·doi:10.1007/s00404-007-0479-1
article 2007
Women with advanced-stage endometriosis and previous surgery respond less well to gonadotropin stimulation, but have similar IVF implantation and delivery rates compared with women with tubal factor infertility
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.01.037
article 2006
Statins Inhibit Growth of Human Endometrial Stromal Cells Independently of Cholesterol Availability1
Biology of reproduction ·doi:10.1095/biolreprod.106.051763

Endometriosis is characterized by ectopic growth of endometrial tissues. Statins, inhibitors of 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMGCR), have been shown to decrease proliferation of several mesenchymal tissues. Actions of sta…

review 2006
The role of endometrium in endometriosis
Journal of the Society for Gynecologic Investigation ·doi:10.1016/j.jsgi.2006.07.005

Endometriosis is defined as the presence of endometrial glands and stroma outside the uterus. Several theories have been proposed to explain the pathogenesis of this disease. According to Sampson's retrograde menstruation theory, endometria…