S H Kennedy

No ORCID on file · 24 papers in corpus · active 1988-2013

Study types

  • article 15
  • other 4
  • review 4
  • rct 1

Condition tags

  • endometriosis 23
  • mesh:D004715 22
  • infertility 3
  • irritable_bowel_syndrome 1
  • chronic_pelvic_pain 1
  • mesh:D017699 1
  • endometrioma 1
  • adenomyosis 1
article 2013
Human Reproduction ·doi:10.1093/humrep/des454

STUDY QUESTION: Are levels of circulating angiogenic cells (CACs) affected by the presence of endometriosis? SUMMARY ANSWER: Levels of CACs are equivalent in women with and without endometriosis. WHAT IS KNOWN ALREADY: Murine models have su…

article 2011
Molecular human reproduction ·doi:10.1093/molehr/gar035

Endometriosis is a common, chronic gynaecological disease affecting up to 10% of women in their reproductive years. Its aetiology still remains unclear, but evidence indicates genetic factors play a role. We previously identified a region o…

other 2011
Human reproduction update ·doi:10.1093/humupd/dmr013

BACKGROUND: Endometriosis is usually diagnosed by an invasive procedure such as a laparoscopy. Great interest therefore lies in the potential to identify biomarkers which may be surrogates of disease presence or activity, especially relatin…

review 2010
Human reproduction update ·doi:10.1093/humupd/dmq009

BACKGROUND: Endometriosis is estimated to affect 1 in 10 women during the reproductive years. There is often delay in making the diagnosis, mainly due to the non-specific nature of the associated symptoms and the need to verify the disease …

article 2001
Molecular human reproduction ·doi:10.1093/molehr/7.11.1073

An association between endometriosis and the glutathione S-transferase (GST) M1 null mutation has been reported in French and Slavic populations. We aimed to replicate this association of endometriosis in a UK population, and to test for as…

review 2001
Current opinion in obstetrics & gynecology ·doi:10.1097/00001703-200106000-00011

Family studies have long suggested a role for genetic factors in the aetiology of endometriosis. The influence of genes on disease development has mainly been researched independently of environmental factors, yet their interaction must pla…

article 1999
Molecular human reproduction ·doi:10.1093/molehr/5.10.990

An association between the N314D polymorphism of galactose-1-phosphate uridyl transferase and endometriosis has recently been reported in a North American population. To determine whether such an association exists in the UK population, we …

review 1999
Gynecologic and obstetric investigation ·doi:10.1159/000052856

Peritoneal fluid is a specific microenvironment. It originates mainly as an ovarian exudation product due to increased vascular permeability, and contains large amounts of macrophages and their secretion products, which include growth facto…

article 1999
British journal of obstetrics and gynaecology ·doi:10.1111/j.1471-0528.1999.tb08141.x

OBJECTIVES: To describe duration of symptoms and patterns of diagnosis and referral in women with chronic pelvic pain. DESIGN: Retrospective cohort analysis of the MediPlus UK Primary Care Database. SETTING: One hundred and thirty-six gener…

review 1998
Human reproduction update ·doi:10.1093/humupd/4.5.741

Peritoneal fluid and the intraovarian milieu are a specific microenvironment. Peritoneal fluid originates mainly as an ovarian exudation product caused by increased vascular permeability, with cyclic variation in volume and steroid hormones…

article 1997
Fertility and Sterility ·doi:10.1016/s0015-0282(97)00359-2
article 1997
Human reproduction update ·doi:10.1093/humupd/3.2.109

The autopsy records between 1980 and 1995 of 399 female rhesus monkeys (Macaca mulatta) at the Wisconsin Regional Primate Research Center were examined. Spontaneous endometriosis was found in 81 (20%) of the animals. The mean (+/- SD) ages …

article 1996
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a019351

An enzyme-linked immunosorbent assay (ELISA) was developed to measure anti-endometrial antibody concentrations in the serum of women with endometriosis. Pooled cytosolic protein extracts from the endometrial gland cells of 10 women were use…

article 1994
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a138623

Journal Article Dioxin pollution and endometriosis in Belgium Get access P.R. Koninckx, P.R. Koninckx 3 1Division of Gynaecologic Endoscopic Surgery, Department of Obstetrics and Gynaecology, University Hospital Gasthuisberg, K.U.LeuvenB–30…

other 1993
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a137897

This study assessed the effects on plasma adrenocorticotrophic hormone (ACTH) and cortisol concentrations of 3 months' treatment with intranasal nafarelin 200 micrograms b.d. in 11 women (aged 26-43 years) for the treatment of endometriosis…

other 1992
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a137850

'Chocolate' fluid aspirated from endometriotic cysts was injected into the peritoneal cavity of mice. No peritoneal adhesions or endometriosis were noted when the animals were killed 7-37 days later.

article 1990
Fertility and Sterility ·doi:10.1016/s0015-0282(16)53574-2
rct 1990
Obstetrics and gynecology

No previous study has investigated prospectively the quantitative effect of treatment on antiendometrial antibody levels in endometriosis. We measured antiendometrial antibody levels by an enzyme-linked immunosorbent assay in 35 women with …

article 1990
British journal of obstetrics and gynaecology ·doi:10.1111/j.1471-0528.1990.tb16235.x

Twenty-eight women with suspected endometriosis or infertility, or both, received radiolabelled monoclonal antibody OC-125 F(ab')2 fragments before surgery in a study to determine whether foci of pelvic endometriosis could be displayed with…

article 1990
British journal of obstetrics and gynaecology ·doi:10.1111/j.1471-0528.1990.tb16236.x

Anti-endometrial antibody binding was localized using a double-labelling immunohistochemical method on frozen sections of endometrium taken from a woman without pelvic disease. Serum from 40 women with endometriosis was tested and, as contr…

article 1989
Fertility and Sterility ·doi:10.1016/s0015-0282(16)53175-6
article 1989
Journal of clinical pathology ·doi:10.1136/jcp.42.12.1272

Among 10 patients with endometriosis CA 125 was increased (greater than 35 U/ml) in endometriotic cyst fluid in all the patients, but only two had increased serum concentrations. Gel electrophoresis of serum, endometriotic cyst fluid, and e…

other 1988
British journal of obstetrics and gynaecology ·doi:10.1111/j.1471-0528.1988.tb06532.x

CA-125 is a membrane antigen detected in the serum of some women with gynaecological disease including endometriosis. We attempted to use a radioiodinated anti-CA-125 monoclonal antibody, OC-125, to image ovarian endometriosis using immunos…

article 1988
British journal of obstetrics and gynaecology ·doi:10.1111/j.1471-0528.1988.tb12810.x