Immunoscintigraphy of ovarian endometriosis. A preliminary study
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Immunoscintigraphy with a radioiodinated anti-CA-125 monoclonal antibody successfully imaged ovarian endometriosis in two women, though sensitivity varied between cases.
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Abstract
CA-125 is a membrane antigen detected in the serum of some women with gynaecological disease including endometriosis. We attempted to use a radioiodinated anti-CA-125 monoclonal antibody, OC-125, to image ovarian endometriosis using immunoscintigraphy. Two women with significant endometriosis and normal serum CA-125 levels had positive immunoscintigraphy. In one woman, all areas of endometriosis were imaged; in the other, endometriosis in one affected ovary was seen, but uptake in the other ovary was less than the extent of the disease.
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- europepmc
- last seen: 2026-10-05T06:18:27.067365+00:00
- pubmed
- last seen: 2026-05-13T22:09:20.810540+00:00
- unpaywall
- last seen: 2026-10-05T06:32:29.880811+00:00
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine