Yali Li

Abnormal development of granulosa cells is widely recognized as a critical factor contributing to polycystic ovary syndrome (PCOS). However, the precise etiology and underlying mechanisms of this disorder remain largely elusive. Accumulatin…

BACKGROUND: Previous clinical trials regarding the therapy in epithelial ovarian tumors have involved patients with all types of ovarian tumors. Mucinous borderline tumors may progress to invasive carcinoma even after therapy and Patients w…

As a traditional Chinese herbal medicine, Panax ginseng C. A. Meyer (PG) has preventive and therapeutic effects on various diseases. Ginsenosides are main active ingredients of PG and have good pharmacological effects. Due to the diversity …

BACKGROUND: Endometriosis (EMs) is a common gynecological disorder characterized by endometrial-like tissue outside the uterus. Hypoxia induces the expression of many important downstream genes to regulate the implantation, survival, and ma…

OBJECTIVE: To determine the effects of hypobaric hypoxia pretreatment on surgically induced endometriosis in rats. METHODS: Six rats were randomized into 2 groups and exposed to hypoxia (8% O2) and normoxia (21% O2) for 8 h. The uterine en…

Cancer induced bone pain is a very complicated clinical pain states that has proven difficult to be treated effectively due to poorly understand of underlying mechanism, but bone cancer pain (BCP) seems to be enhanced by a state of spinal s…

OBJECTIVE: This study measured the human epididymis protein 4 (HE4) and CA125 levels in Chinese women with benign gynecological disorders. MATERIAL AND METHODS: Sera were obtained from Chinese women prior to surgery for a pelvic mass and H…

OBJECTIVE: To evaluate the effects of lesion location on adhesion and angiogenesis of transplanted endometriotic lesions in SCID mice. METHODS: Three groups of female SCID mice included intraperitoneal (i.p.) (n = 12), subcutaneous (s.c.) …

OBJECTIVE: To investigate the effects of oxygen on the proliferation and angiogenesis of endometriosis in vivo. DESIGN: Animal studies. SETTING: Animal research facility. ANIMAL(S): Thirty-six female severe combined immunodeficiency (SCI…

Endometriosis is a complex and enigmatic disease that arises from the interplay among multiple genetic and environmental factors. The defining feature of endometriosis is the deposition and growth of endometrial tissues at sites outside of …

AIM: To analyze the composition of the Chinese herbal medicine Sanjie Zhentong Capsule (SJZTC) and test the therapeutic efficacy of each component in a rat model of endometriosis. METHODS: A rapid resolution liquid chromatography (RRLC) me…

Rhodiola can enhance nonspecific immune system function,which is considered as adaptogen due to its multiple functions such as anti-hypoxic and estrogen-like properties.This review demonstrates the pharmacological mechanisms of Rhodiola whi…

OBJECTIVE: To determine the effects of carbon dioxide (CO(2)) and nitrogen (N(2)) pneumoperitoneums on endometriosis (EMs) lesions. METHODS: Female Wistar rats were randomized into the following 3 groups: CO(2) (N = 20), N(2) (N = 22) and …

OBJECTIVE: To investigate the expression of the anti-oncogene ARHI in the endometriotic tissue and explore its clinical significance. METHODS: A semiquantitative analysis of the expression of ARHI mRNA and protein in the ectopic and eutopi…

Objective To analyze the effect of laparoscopic excision on deep infiltrating type endometriosis(DIE) in posterior pelvis.Methods Data of 35 cases of posterior pelvic DIE admitted to General Hospital of PLA from Jan.2006 to Jan.2009 were re…

OBJECTIVE: To establish a diagnostic model of endometriosis by analyzing serum peptidome patterns in patients with endometriosis using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS). METHODS: Se…

Objective To study the application of hysteroscopy combined with laparoscopy in operation of patients with gynecological diseases and its indications.Methods Data about 236 patients who underwent operation by hysteroscopy combined with lapa…

Objective To set up an experimental endometriosis model using ER-β knockout mice,and to investigate the role of ER-β in the pathogenesis of endometriosis.Methods Autotransplantation of uterine tissue to ectopic sites in the abdominal wall w…

Objective To investigate the expression of gonadotropin-releasing hormone (GnRH) and its receptor (GnRH-R) in human endometriosis (EMS) and normal endometrial cells cultured in vitro. Methods Fresh eutopic endometrial specimens were collect…

OBJECTIVE: To investigate the distribution of ER isoforms in endometriosis and eutopic endometrium. METHODS: Tissue samples of patients with ovarian endometriosis, treated in People's Liberation Army General Hospital from January 2004 to D…

BACKGROUND: Direct and indirect evidences have suggested that angiogenesis is a prerequisite for the development of endometriosis. Aiming at offering experimental evidences for anti-angiogenesis therapy, we transplanted the eutopic endometr…

Objective:To find out the diagnostic value of ultrasonography to endometriosis.Methods:To retrospectively analyse the results of ultrasonography of 90 cases who were finally diagnosed by laparoscopy before operation.And compare ultrasonogra…

Objective:To detect the expression of vascular endothelial growth factor receptors(VEGFR)flt-1 and KDR mRNA in the ectopic and eutopic endometrium of patients with endometriosis.Methods:44 specimens of ovarian endometrioma and 30 eutopic en…