Wu J

BACKGROUND: Aspartame, a widely used artificial sweetener, has been implicated in multiple toxicities. However, its potential reproductive toxicity mechanisms remain unclear. This study aimed to investigate the underlying relationship betwe…

BACKGROUND: Recent studies have disputed the association between bisphenol A (BPA) and endometriosis. This updated meta-analysis was conducted to investigate the impact of BPA exposure on endometriosis. METHODS: This study evaluated BPA ex…

Poly (ADP-ribose) polymerase (PARP) inhibitors have emerged as a paradigm-shifting therapeutic strategy in oncology, demonstrating significant synthetic lethality in tumors characterized by homologous recombination deficiency. Due to their …

This study aims to investigate the effects of different transfer strategies (blastocyst vs cleavage-stage embryo) on the cumulative live birth rate (CLBR) and perinatal outcomes. In this propensity score matching (PSM) study, we evaluated t…

BackgroundSarcopenia is the progressive, widespread loss of skeletal muscle mass, strength, and function, which happens as a result of aging. This study aims to analyze the alterations in serum protein profiles and explore a biomarker of di…

BackgroundFollicular fluid extracellular vesicles (EVs) have emerged as critical mediators of intercellular communication during oocyte development. This study investigates the role of small non-coding RNAs (SncRNAs) within porcine follicul…

ObjectiveTo evaluate the association between prior mode of delivery (cesarean vs. vaginal) and endometrial thickness in the subsequent frozen embryo transfer (FET) cycle. The secondary aim was to evaluate FET cycle outcomes.DesignRetrospect…

BACKGROUND: The gamma-glutamyl transferase (GGT) to high-density lipoprotein (HDL) ratio (GGT/HDL) has recently emerged as a potential biomarker for metabolic and liver diseases. This study aimed to investigate the association between GGT/H…

Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues to varying degrees. T…

BACKGROUND: Endometrial receptivity (ER) serves as a critical determinant for successful embryo implantation, yet its molecular complexity and limited clinical assessment methods pose significant challenges. Despite advancements in assisted…

Clinical application of mesenchymal stem cells for endometrial repair has been hampered by variability in cell quality, large-scale production, and uncertainty regarding the optimal delivery route. In this study, we investigated the therape…

OBJECTIVE: To assess the safety and efficacy of percutaneous intrauterine hydrodissection as a protective technique during microwave ablation (MWA) of uterine fibroids adjacent to the endometrium. MATERIALS AND METHODS: A retrospective ana…

BackgroundImplantation failure is the most common cause of pregnancy failure and is a major limiting factor in assisted reproduction. Plasma microRNA (miRNA) expression profiles show dynamic changes among individuals with successful implant…

This study investigated fertility-related quality of life among married women of reproductive age (20-45 years) with endometriosis-associated infertility, focusing on the mediating role of family resilience between infertility-related stres…

BackgroundPolycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by ovulatory dysfunction and hormonal imbalance, often leading to infertility. Cangfu Daotan Decoction (CFDTT, Atractylodis Rhizoma, Cyperi Rhizoma, Pin…

ObjectiveAtypical glandular cells (AGC) in cervical cytology are often ignored, and the malignancy risk associated with AGC remains uncertain. This study aims to evaluate the histopathology and clinical correlations in patients diagnosed wi…

BackgroundThe ciliary muscle, a critical intraocular smooth muscle, plays a potent role in ocular accommodation. Investigating the potential detrimental effects on the ciliary muscle during prolonged contraction and precise mechanism underl…

ETHNOPHARMACOLOGICAL RELEVANCE: Xiao-Liu Tang (XLT), a formulation grounded in the Traditional Chinese medicine (TCM) theory of Qi-Blood, has shown promise in alleviating endometriosis-related symptoms through clinical observations, with em…

INTRODUCTION: This study aimed to explore the feasibility and safety of robotic single port vaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) hysterectomy when compared with traditional vaginal natural orifice translumina…

Polycystic ovary syndrome is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression. However, the underlying mechanism remains unc…

BackgroundOrganochlorine pesticides (OCPs) are extensively dispersed throughout the environment, which potentially have harmful impacts on the female reproductive system. Therefore, the purpose of this study was to clarify the association b…

BackgroundVisceral fat accumulation and dyslipidaemia are associated with infertility symptoms. The cardiometabolic index (CMI) is a comprehensive quantitative measure of central obesity and dyslipidaemia. However, the link between the fema…

INTRODUCTION: Endometriosis (EMS) is a common gynaecological disorder linked to metabolic disturbances. However, evidence on the associations between lipid accumulation product (LAP) and visceral adiposity index (VAI) with the risk of EMS r…

BackgroundThis study was aimed at evaluating the postoperative outcomes of vaginal natural orifice transluminal endoscopic hysterectomy (vNOTEH).MethodsThis prospective cohort study was conducted for comparing recovery outcomes, the time to…

Distinct PAEs are implicated in breast cancer progression through multiple molecular pathways. This study aims to elucidate the potential mechanisms in common by which PAEs promote breast cancer progression. Dibutyl phthalate (DBP), benzyl …