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Study questionDoes endometrial gene expression change across consecutive cycles and after endometrial injury?Summary answerAlthough paired endometrial samples collected from the same woman across two consecutive cycles show greater similari…
The dynamic nature of human endometrial tissue presents unique challenges in analysis. Despite extensive research into endometrial disorders such as endometriosis and infertility, recent systematic reviews have highlighted concerning issues…
BACKGROUND: Despite surgical and pharmacological interventions, endometriosis can recur. Reliable information regarding risk of recurrence following a first diagnosis is scant. The aim of this study was to examine clinical and survey data i…
Natural variability in menstrual cycle length, coupled with rapid changes in endometrial gene expression, makes it difficult to accurately define and compare different stages of the endometrial cycle. Here we develop and validate a method f…
Endometriosis is a complex disease, influenced by genetic factors. Genetic markers associated with endometriosis exist at chromosome 1p36.12 and lead to altered expression of the long intergenic non-coding RNA 339 (LINC00339), however, the …
Research questionDoes obesity affect endometrial gene expression in women with endometriosis, specifically women with stage I disease?DesignDifferential gene expression analysis was conducted on endometrium from women with and without endom…