Jacqueline F. Donoghue

ORCID: 0000-0003-1370-2469 · 20 papers in corpus · active 2002-2025

Study types

  • article 15
  • other 2
  • review 2
  • meta-analysis 1

Condition tags

  • endometriosis 14
  • adenomyosis 3
  • dysmenorrhea 1
  • infertility 1
  • dyspareunia 1
  • irritable_bowel_syndrome 1
  • chronic_pelvic_pain 1
other 2025
Journal of cannabis research ·doi:10.1186/s42238-025-00275-x

BACKGROUND: Endocannabinoids are small lipid molecules that have critical roles in cellular proliferation and function. They are produced locally with their concentrations controlled via the endocannabinoid system (ECS). The important cellu…

article 2024
BMC medicine ·doi:10.1186/s12916-024-03508-7

BACKGROUND: Despite surgical and pharmacological interventions, endometriosis can recur. Reliable information regarding risk of recurrence following a first diagnosis is scant. The aim of this study was to examine clinical and survey data i…

article 2023
Nature communications ·doi:10.1038/s41467-023-41979-z

Natural variability in menstrual cycle length, coupled with rapid changes in endometrial gene expression, makes it difficult to accurately define and compare different stages of the endometrial cycle. Here we develop and validate a method f…

meta-analysis 2023
Nature genetics ·doi:10.1038/s41588-023-01323-z

Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genom…

article 2023
Biomolecules ·doi:10.3390/biom13060965

Endometriosis, defined as the growth of hormonally responsive endometrial-like tissue outside of the uterine cavity, is an estrogen-dependent, chronic, pro-inflammatory disease that affects up to 11.4% of women of reproductive age and gende…

other 2022
Scientific reports ·doi:10.1038/s41598-022-13488-4

Endocannabinoids mediate cellular functions and their activity is controlled by a complex system of enzymes, membrane receptors and transport molecules. Endocannabinoids are present in endometrium, a cyclical regenerative tissue requiring t…

article 2021
Molecular human reproduction ·doi:10.1093/molehr/gaab010

Endometriosis is a complex disease, influenced by genetic factors. Genetic markers associated with endometriosis exist at chromosome 1p36.12 and lead to altered expression of the long intergenic non-coding RNA 339 (LINC00339), however, the …

review 2021
Frontiers in reproductive health ·doi:10.3389/frph.2021.729642

Endometriosis-associated pain and the mechanisms responsible for its initiation and persistence are complex and difficult to treat. Endometriosis-associated pain is experienced as dysmenorrhea, cyclical pain related to organ function includ…

article 2020
article 2020
Reproduction, fertility, and development ·doi:10.1071/rd19449

The 2019 meeting of the Society for Reproductive Biology (SRB) provided a platform for the dissemination of new knowledge and innovations to improve reproductive health in humans, enhance animal breeding efficiency and understand the effect…

article 2020
article 2019
Molecular human reproduction ·doi:10.1093/molehr/gaz006

Endometriotic lesions are composed in part of endometrial-like stromal cells, however, there is a shortage of immortalized human endometrial stromal cultures available for research. As genetic factors play a role in endometriosis risk, it i…

article 2019
article 2019
review 2008
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719108325509
article 2008
article 2006
The Australian & New Zealand journal of obstetrics & gynaecology ·doi:10.1111/j.1479-828x.2006.00546.x

BACKGROUND: Activin is a well-characterised growth and differentiation factor and an important inflammatory mediator. Activin is secreted by normal endometrial glands and stroma and is expressed by endometrial leucocytes. It is also known t…

article 2006
article 2005
·doi:10.1071/srb05abs285

Information on uterine lymphatics is limited. The aim of this study was to characterise uterine lymphatic vessels and the corresponding growth factors in the endometrium and myometrium across the normal human menstrual cycle. Uterine tissue…

article 2002
·doi:10.1016/s0015-0282(01)03152-1