Grant W Montgomery

No ORCID on file · 206 papers in corpus · active 2002-2026

Study types

  • article 115
  • other 24
  • review 23
  • preprint 10
  • meta-analysis 4

Condition tags

  • endometriosis 180
  • infertility 22
  • chronic_pelvic_pain 7
  • adenomyosis 5
  • dysmenorrhea 4
  • irritable_bowel_syndrome 3
  • die_deep_infiltrating 2
  • endometrioma 1
preprint 2022
·doi:10.1101/2022.11.27.518106

Abstract Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Identifying biologic and genetic effects on DNA methylation (DNAm) in endometrium increases understanding of mechanisms that influence g…

other 2022
Annals of epidemiology ·doi:10.1016/j.annepidem.2021.10.005

PURPOSE: Endometriosis is a chronic inflammatory disease affecting the reproductive, gastrointestinal, and urinary systems. We examined changes in labor force participation amongst women with endometriosis following diagnosis. METHODS: We …

preprint 2021
·doi:10.21203/rs.3.rs-596345/v1

Abstract Cellular development is tightly regulated as mature cells with aberrant functions may initiate pathogenic processes. The endometrium is a highly regenerative tissue, shedding and regenerating each month. Endometrial stromal fibrob…

preprint 2021
·doi:10.1101/2021.06.28.21259290

Abstract Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Data from large endometriosis and EOC genome-wide association meta-analyses were used to estimate the genetic correlation and evaluate the causal…

other 2021
Journal of personalized medicine ·doi:10.3390/jpm11121314

Endometrial organoids (EMO) are an important tool for gynecological research but have been limited by generation from (1) invasively acquired tissues and thus advanced disease states and (2) from women who are not taking hormones, thus excl…

article 2021
Molecular human reproduction ·doi:10.1093/molehr/gaab010

Endometriosis is a complex disease, influenced by genetic factors. Genetic markers associated with endometriosis exist at chromosome 1p36.12 and lead to altered expression of the long intergenic non-coding RNA 339 (LINC00339), however, the …

other 2021
Human genetics ·doi:10.1007/s00439-021-02312-0

Endometriosis, polycystic ovary syndrome (PCOS) and uterine fibroids have been proposed as endometrial cancer risk factors; however, disentangling their relationships with endometrial cancer is complicated due to shared risk factors and com…

review 2021
Human Reproduction ·doi:10.1093/humrep/deab254

STUDY QUESTION: Is there a shared genetic or causal association of endometriosis with asthma or what biological mechanisms may underlie their potential relationships? SUMMARY ANSWER: Our results confirm a significant but non-causal associat…

article 2021
Frontiers in reproductive health ·doi:10.3389/frph.2021.711123

Epidemiological studies have observed that risk of endometriosis is associated with history of cutaneous melanoma and vice versa. Evidence for shared biological mechanisms between the two traits is limited. The aim of this study was to inve…

article 2021
Science translational medicine ·doi:10.1126/scitranslmed.abd6469

< 0.05) in a mouse model of peritoneal inflammation as well as in a mouse model of endometriosis. We conclude that the NPSR1/NPS system is a genetically validated, nonhormonal target for the treatment of endometriosis with likely increased …

article 2021
·doi:10.60692/cc0mb-05224

Introduction Endometriosis is one of the common, gynaecological disorders associated with chronic pelvic pain and subfertility affecting ~10% of reproductive age women. The clinical presentation, etiopathogenesis of endometriosis subtypes a…

article 2021
·doi:10.60692/4p81f-2zh03

Introduction Endometriosis is one of the common, gynaecological disorders associated with chronic pelvic pain and subfertility affecting ~10% of reproductive age women. The clinical presentation, etiopathogenesis of endometriosis subtypes a…

article 2021
BMJ open ·doi:10.1136/bmjopen-2021-050844

INTRODUCTION: Endometriosis is one of the common, gynaecological disorders associated with chronic pelvic pain and subfertility affecting ~10% of reproductive age women. The clinical presentation, etiopathogenesis of endometriosis subtypes …

letter 2020
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2020.04.021
review 2020
Seminars in reproductive medicine ·doi:10.1055/s-0040-1713429

Endometriosis remains an enigmatic disease of unknown etiology, with delayed diagnosis and poor therapeutic options. This review will discuss the cellular, physiological, and genomic evidence of Sampson's hypothesis of retrograde menstruati…

article 2020
preprint 2020
·doi:10.1101/2020.11.09.20228114

Abstract Endometriosis, polycystic ovary syndrome (PCOS) and uterine fibroids have been proposed as endometrial cancer risk factors; however, disentangling their relationships with endometrial cancer is complicated due to shared risk factor…

article 2020
Human genetics ·doi:10.1007/s00439-020-02223-6

Evidence from observational studies indicates that endometriosis and depression often co-occur. However, conflicting evidence exists, and the etiology as well as biological mechanisms underlying their comorbidity remain unknown. Utilizing g…

article 2020
article 2020
Molecular human reproduction ·doi:10.1093/molehr/gaaa082

The etiology and pathogenesis of endometriosis are complex with both genetic and environmental factors contributing to disease risk. Genome-wide association studies (GWAS) have identified multiple signals in the estrogen receptor 1 (ESR1) r…

article 2020
article 2020
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2020.03.015

Research questionDoes obesity affect endometrial gene expression in women with endometriosis, specifically women with stage I disease?DesignDifferential gene expression analysis was conducted on endometrium from women with and without endom…

article 2020
BJOG: An International Journal of Obstetrics & Gynaecology ·doi:10.1111/1471-0528.16447

OBJECTIVE: To estimate the prevalence and incidence of endometriosis among Australian women. DESIGN: Population-based cohort study linked to administrative health records. SETTING: Secondary analysis of seven surveys collected between 2000 …

review 2020
Genes ·doi:10.3390/genes11030268

Observational epidemiological studies indicate that endometriosis and migraine co-occur within individuals more than expected by chance. However, the aetiology and biological mechanisms underlying their comorbidity remain unknown. Here we e…

2020
Nature communications ·doi:10.1038/s41467-020-19742-5

Miscarriage is a common, complex trait affecting ~15% of clinically confirmed pregnancies. Here we present the results of large-scale genetic association analyses with 69,054 cases from five different ancestries for sporadic miscarriage, 75…